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LMNA lamin A/C [ Pan troglodytes (chimpanzee) ]

Gene ID: 457385, updated on 3-Apr-2024

Summary

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Official Symbol
LMNAprovided by VGNC
Official Full Name
lamin A/Cprovided by VGNC
Primary source
VGNC:VGNC:11515
Locus tag
CK820_G0041294
See related
Ensembl:ENSPTRG00000001447
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (93057437..93114620, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (138266853..138292295)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA26 Neighboring gene semaphorin 4A Neighboring gene mex-3 RNA binding family member A Neighboring gene RAB25, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome. Sakate R, et al. Gene, 2007 Sep 1. PMID 17574350

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear envelope organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear pore localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear lamina IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lamin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098554.1 → NP_001092024.1  lamin

    See identical proteins and their annotated locations for NP_001092024.1

    Status: PROVISIONAL

    Source sequence(s)
    AB222149
    UniProtKB/TrEMBL
    A0A2I3RZP7, A0A2J8K546, A0A6D2W9Z9, A5A6M1
    Related
    ENSPTRP00000002448.5, ENSPTRT00000002663.5
    Conserved Domains (5) summary
    pfam00038
    Location:30 → 386
    Filament; Intermediate filament protein
    pfam00932
    Location:433 → 541
    LTD; Lamin Tail Domain
    pfam05384
    Location:32 → 119
    DegS; Sensor protein DegS
    pfam09798
    Location:302 → 463
    LCD1; DNA damage checkpoint protein
    pfam10018
    Location:191 → 355
    Med4; Vitamin-D-receptor interacting Mediator subunit 4

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    93057437..93114620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063785594.1 → XP_063641664.1  lamin isoform X1

    UniProtKB/TrEMBL
    A0A2J8K531, A0A6D2WTG6, H2Q091

  2. XM_063785564.1 → XP_063641634.1  lamin isoform X1

    UniProtKB/TrEMBL
    A0A2J8K531, A0A6D2WTG6, H2Q091

  3. XM_016959917.3 → XP_016815406.1  lamin isoform X2

    UniProtKB/TrEMBL
    A0A2I3RW42, A0A2J8K542, A0A6D2WER0
    Related
    ENSPTRP00000082161.1
    Conserved Domains (3) summary
    pfam00932
    Location:321 → 429
    LTD; Lamin Tail Domain
    pfam09798
    Location:190 → 351
    LCD1; DNA damage checkpoint protein
    pfam10018
    Location:79 → 243
    Med4; Vitamin-D-receptor interacting Mediator subunit 4

  4. XM_054656299.2 → XP_054512274.1  lamin isoform X3

  5. XM_054656324.2 → XP_054512299.1  lamin isoform X4

    UniProtKB/TrEMBL
    A0A2I3SYV6, A0A2J8K535, A0A6D2Y342
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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