PMVK phosphomevalonate kinase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PMVKprovided by VGNC
Official Full Name: phosphomevalonate kinaseprovided by VGNC
Primary source: VGNC:VGNC:1461
Locus tag: CK820_G0045190
See related: Ensembl:ENSPTRG00000001393
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (94250049..94267961)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (137081775..137099710, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

WI-14846 (e-PCR)
- UniSTS:15801

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phosphomevalonate kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cholesterol biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in isopentenyl diphosphate biosynthetic process, mevalonate pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphomevalonate kinase

XP_009431180.2

EC 2.7.4.2

XP_016783578.1

EC 2.7.4.2

XP_016783589.1

EC 2.7.4.2

XP_016783597.1

EC 2.7.4.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

94250049..94267961

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016928100.4 → XP_016783589.1 phosphomevalonate kinase isoform X1

Conserved Domains (1) summary

cl04466
Location:1 → 111

P-mevalo_kinase; Phosphomevalonate kinase
XM_016928089.3 → XP_016783578.1 phosphomevalonate kinase isoform X2

UniProtKB/TrEMBL

A0A2J8Q351, A0A6D2W7A6, H2Q057, K7AWU9

Related

ENSPTRP00000002347.6

Conserved Domains (1) summary

pfam04275
Location:14 → 123

P-mevalo_kinase; Phosphomevalonate kinase
XM_009432905.4 → XP_009431180.2 phosphomevalonate kinase isoform X1

Conserved Domains (1) summary

cl04466
Location:1 → 111

P-mevalo_kinase; Phosphomevalonate kinase
XM_016928108.4 → XP_016783597.1 phosphomevalonate kinase isoform X3

Conserved Domains (1) summary

pfam04275
Location:16 → 109

P-mevalo_kinase; Phosphomevalonate kinase