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CTSK cathepsin K [ Pan troglodytes (chimpanzee) ]

Gene ID: 457278, updated on 29-Mar-2024

Summary

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Official Symbol
CTSKprovided by VGNC
Official Full Name
cathepsin Kprovided by VGNC
Primary source
VGNC:VGNC:515
Locus tag
CK820_G0046970
See related
Ensembl:ENSPTRG00000001265
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (98404833..98418903)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (132930834..132944306, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene cytochrome c Neighboring gene aryl hydrocarbon receptor nuclear translocator Neighboring gene U6 spliceosomal RNA Neighboring gene short coiled-coil protein-like Neighboring gene cathepsin S

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cathepsin K
XP_001171151.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    98404833..98418903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001171151.7 → XP_001171151.1  cathepsin K

    See identical proteins and their annotated locations for XP_001171151.1

    UniProtKB/TrEMBL
    A0A2J8JJ73, A0A2J8JJ81, A0A6D2WAY7, H2PZX4
    Related
    ENSPTRP00000002145.5
    Conserved Domains (2) summary
    smart00848
    Location:26 → 85
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:115 → 327
    Peptidase_C1; Papain family cysteine protease
Nucleotide Protein
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