APH1A aph-1 homolog A, gamma-secretase subunit [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: APH1Aprovided by VGNC
Official Full Name: aph-1 homolog A, gamma-secretase subunitprovided by VGNC
Primary source: VGNC:VGNC:91
Locus tag: CK820_G0046945
See related: Ensembl:ENSPTRG00000001250
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (98952937..98956545)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (132393192..132396800, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SGC31751 (e-PCR)
- UniSTS:5665

CA14_9388 (e-PCR)
- UniSTS:468313

MARC_7139-7140:992008251:1 (e-PCR)
- UniSTS:231303

MARC_7139-7140:996687542:1 (e-PCR)
- UniSTS:231303

APH-1A__4340 (e-PCR)
- UniSTS:462736

D13S1659 (e-PCR)
- UniSTS:81328

SHGC-32182 (e-PCR)
- UniSTS:7100

A004F41 (e-PCR)
- UniSTS:47312

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch receptor processing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of catalytic activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein processing	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
part_of gamma-secretase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: gamma-secretase subunit APH-1A

Names: APH1A gamma secretase subunit; anterior pharynx defective 1 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.