NOTCH2 notch receptor 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Gene symbol: NOTCH2
Gene description: notch receptor 2
Locus tag: CK820_G0044320
See related: Ensembl:ENSPTRG00000048364
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 39

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (117066327..117292386, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (114057353..114218496)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-75405 (e-PCR)
- UniSTS:10001

Cda0hb04 (e-PCR)
- UniSTS:35355

NOTCH2_1357 (e-PCR)
- UniSTS:277535

SHGC-75400 (e-PCR)
- UniSTS:26191

SHGC-152728 (e-PCR)
- UniSTS:184937

D1S2696 (e-PCR)
- UniSTS:211

G19892 (e-PCR)
- UniSTS:76761

A002B26 (e-PCR)
- UniSTS:76762

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Notch binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to tumor cell	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of developmental process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: neurogenic locus notch homolog protein 2

Names: NBPF14; notch 2; notch homolog 2 N-terminal-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

117066327..117292386 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063815783.1 → XP_063671853.1 neurogenic locus notch homolog protein 2 isoform X5
XM_054668958.2 → XP_054524933.1 neurogenic locus notch homolog protein 2 isoform X2
XM_054668954.2 → XP_054524929.1 neurogenic locus notch homolog protein 2 isoform X1

UniProtKB/TrEMBL

K7C726
XM_054668956.2 → XP_054524931.1 neurogenic locus notch homolog protein 2 isoform X2
XM_054668960.2 → XP_054524935.1 neurogenic locus notch homolog protein 2 isoform X3
XM_054668971.2 → XP_054524946.1 neurogenic locus notch homolog protein 2 isoform X6
XM_054668968.2 → XP_054524943.1 neurogenic locus notch homolog protein 2 isoform X4