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CSF1 colony stimulating factor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 457127, updated on 3-Apr-2024

Summary

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Official Symbol
CSF1provided by VGNC
Official Full Name
colony stimulating factor 1provided by VGNC
Primary source
VGNC:VGNC:510
Locus tag
CK820_G0043727
See related
Ensembl:ENSPTRG00000001066
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (121270159..121290658, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (110008994..110029125)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene striatin interacting protein 1 Neighboring gene adenosylhomocysteinase like 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like Neighboring gene EPS8 signaling adaptor L3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in osteoclast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
macrophage colony-stimulating factor 1
Names
colony stimulating factor 1 (macrophage)
XP_003308390.1
XP_009428123.1
XP_016781432.1
XP_016781434.1
XP_016781435.1
XP_016781438.1
XP_063654716.1
XP_063654724.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    121270159..121290658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063798646.1 → XP_063654716.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8JXK5, A0A6D2WKG3, H2PZL7

  2. XM_009429848.4 → XP_009428123.1  macrophage colony-stimulating factor 1 isoform X2

    See identical proteins and their annotated locations for XP_009428123.1

    UniProtKB/TrEMBL
    A0A2I3SSY9, A0A2J8JXK5, A0A6D2WKG3, H2PZL7
    Related
    ENSPTRP00000001844.5
    Conserved Domains (2) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)
    cl28033
    Location:194 → 491
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  3. XM_063798654.1 → XP_063654724.1  macrophage colony-stimulating factor 1 isoform X3

  4. XM_003308342.4 → XP_003308390.1  macrophage colony-stimulating factor 1 isoform X5

    See identical proteins and their annotated locations for XP_003308390.1

    UniProtKB/TrEMBL
    A0A2J8JXJ3, A0A8I3B3Y3, K7ADZ4, K7D7H6
    Conserved Domains (1) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)

  5. XM_016925946.4 → XP_016781435.1  macrophage colony-stimulating factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SSY9

  6. XM_016925943.4 → XP_016781432.1  macrophage colony-stimulating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3RZE8, A0A2I3SSY9

  7. XM_016925949.4 → XP_016781438.1  macrophage colony-stimulating factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SSY9, A0A2J8JXK5, A0A6D2WKG3, H2PZL7
    Related
    ENSPTRP00000068399.1
    Conserved Domains (2) summary
    pfam05337
    Location:41 → 180
    CSF-1; Macrophage colony stimulating factor-1 (CSF-1)
    cl28033
    Location:194 → 491
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  8. XM_016925945.4 → XP_016781434.1  macrophage colony-stimulating factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3RZE8, A0A2I3SSY9
    Related
    ENSPTRP00000070067.1
Nucleotide Protein
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