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PKN2 protein kinase N2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 456998, updated on 29-Mar-2024

Summary

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Official Symbol
PKN2provided by VGNC
Official Full Name
protein kinase N2provided by VGNC
Primary source
VGNC:VGNC:1457
Locus tag
CK820_G0020577
See related
Ensembl:ENSPTRG00000000931
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (142279524..142431416, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (88867872..89019759)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129138509 Neighboring gene elongin-C-like Neighboring gene U6 spliceosomal RNA Neighboring gene general transcription factor IIB Neighboring gene uncharacterized LOC100615600 Neighboring gene uncharacterized LOC134810836

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase N2
XP_001145367.1
XP_003949503.1
XP_016777448.1
XP_063672993.1
XP_063672994.1
XP_513539.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    142279524..142431416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001145367.5 → XP_001145367.1  serine/threonine-protein kinase N2 isoform X1

    See identical proteins and their annotated locations for XP_001145367.1

    UniProtKB/TrEMBL
    A0A2I3TXC6, A0A2J8MH23, A0A6D2X184, H2PZC4
    Related
    ENSPTRP00000001607.3
    Conserved Domains (5) summary
    cd08687
    Location:390 → 473
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:657 → 982
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:130 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

  2. XM_063816924.1 → XP_063672994.1  serine/threonine-protein kinase N2 isoform X6

  3. XM_016921959.4 → XP_016777448.1  serine/threonine-protein kinase N2 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TXC6

  4. XM_063816923.1 → XP_063672993.1  serine/threonine-protein kinase N2 isoform X5

  5. XM_513539.7 → XP_513539.3  serine/threonine-protein kinase N2 isoform X2

    See identical proteins and their annotated locations for XP_513539.3

    UniProtKB/TrEMBL
    A0A2I3TXC6
    Conserved Domains (6) summary
    cd08687
    Location:364 → 457
    C2_PKN-like; C2 domain in Protein kinase C-like (PKN) proteins
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    smart00220
    Location:646 → 900
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05589
    Location:641 → 966
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:130 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

  6. XM_003949454.5 → XP_003949503.1  serine/threonine-protein kinase N2 isoform X3

    See identical proteins and their annotated locations for XP_003949503.1

    UniProtKB/TrEMBL
    A0A2I3TQU2, A0A2I3TXC6, A0A2J8MH20, A0A6D2Y1L8
    Related
    ENSPTRP00000091611.1
    Conserved Domains (5) summary
    cd11622
    Location:42 → 107
    HR1_PKN_1; First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
    cd11635
    Location:209 → 282
    HR1_PKN2_3; Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
    cd05589
    Location:609 → 934
    STKc_PKN; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase N
    cl00087
    Location:130 → 201
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    cl14603
    Location:390 → 472
    C2; C2 domain
Nucleotide Protein
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