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PTPRU protein tyrosine phosphatase receptor type U [ Pan troglodytes (chimpanzee) ]

Gene ID: 456692, updated on 3-Apr-2024

Summary

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Official Symbol
PTPRUprovided by VGNC
Official Full Name
protein tyrosine phosphatase receptor type Uprovided by VGNC
Primary source
VGNC:VGNC:9890
Locus tag
CK820_G0048704
See related
Ensembl:ENSPTRG00000000447
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (201658116..201748287, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (29551006..29641178)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129143191 Neighboring gene uncharacterized LOC134807796 Neighboring gene uncharacterized LOC107975865 Neighboring gene uncharacterized LOC107975866 Neighboring gene mitochondrial trans-2-enoyl-CoA reductase Neighboring gene serine and arginine rich splicing factor 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase U
XP_016813217.1
XP_016813221.1
XP_016813223.1
XP_016813225.1
XP_016813230.1
XP_016813238.1
XP_016813245.1
XP_016813251.1
XP_016813255.1
XP_016813258.1
XP_016813261.1
XP_024213222.1
XP_054520966.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    201658116..201748287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016957756.3 → XP_016813245.1  receptor-type tyrosine-protein phosphatase U isoform X7

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCJ0, A0A2J8JCK4, A0A6D2YC00, A0A803KHV9, K7DAJ5
    Conserved Domains (4) summary
    smart00137
    Location:22 → 186
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    cd00047
    Location:913 → 1130
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:386 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:494 → 577
    fn3; Fibronectin type III domain

  2. XM_016957749.3 → XP_016813238.1  receptor-type tyrosine-protein phosphatase U isoform X6

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A2J8JCL0, A0A6D2VVU3, A0A6D2YC00, H2R469, K7DTJ4
    Related
    ENSPTRP00000046670.6
    Conserved Domains (5) summary
    smart00137
    Location:22 → 186
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    cd00047
    Location:1195 → 1428
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:386 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:494 → 577
    fn3; Fibronectin type III domain
    pfam00102
    Location:908 → 1133
    Y_phosphatase; Protein-tyrosine phosphatase

  3. XM_016957734.3 → XP_016813223.1  receptor-type tyrosine-protein phosphatase U isoform X3

    UniProtKB/TrEMBL
    A0A2I3S535, A0A2I3SEZ5, A0A2I3TPD8, A0A2J8JCK1, A0A2J8JCK4, A0A6D2VXE6, A0A6D2YC00
    Related
    ENSPTRP00000090811.1
    Conserved Domains (5) summary
    smart00137
    Location:22 → 186
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    cd00047
    Location:1205 → 1438
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:386 → 481
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:494 → 577
    fn3; Fibronectin type III domain
    pfam00102
    Location:918 → 1143
    Y_phosphatase; Protein-tyrosine phosphatase

  4. XM_016957769.4 → XP_016813258.1  receptor-type tyrosine-protein phosphatase U isoform X9

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  5. XM_016957766.4 → XP_016813255.1  receptor-type tyrosine-protein phosphatase U isoform X8

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  6. XM_016957741.4 → XP_016813230.1  receptor-type tyrosine-protein phosphatase U isoform X5

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00
    Related
    ENSPTRP00000075554.1

  7. XM_016957736.4 → XP_016813225.1  receptor-type tyrosine-protein phosphatase U isoform X4

    UniProtKB/TrEMBL
    A0A2I3S535, A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  8. XM_016957732.4 → XP_016813221.1  receptor-type tyrosine-protein phosphatase U isoform X2

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  9. XM_016957728.4 → XP_016813217.1  receptor-type tyrosine-protein phosphatase U isoform X1

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  10. XM_016957762.4 → XP_016813251.1  receptor-type tyrosine-protein phosphatase U isoform X10

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00

  11. XM_024357454.3 → XP_024213222.1  receptor-type tyrosine-protein phosphatase U isoform X13

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00
    Conserved Domains (4) summary
    cd00047
    Location:930 → 1163
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:121 → 216
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:229 → 312
    fn3; Fibronectin type III domain
    pfam00102
    Location:643 → 868
    Y_phosphatase; Protein-tyrosine phosphatase

  12. XM_054664991.2 → XP_054520966.1  receptor-type tyrosine-protein phosphatase U isoform X12

  13. XM_016957772.4 → XP_016813261.1  receptor-type tyrosine-protein phosphatase U isoform X11

    UniProtKB/TrEMBL
    A0A2I3SEZ5, A0A2J8JCK4, A0A6D2YC00
Nucleotide Protein
Heading Accession and Version

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