CDC42 cell division cycle 42 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CDC42provided by VGNC
Official Full Name: cell division cycle 42provided by VGNC
Primary source: VGNC:VGNC:57714
Locus tag: CK820_G0041658
See related: Ensembl:ENSPTRG00000051031
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (208926162..208987577, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (22332932..22373134)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SHGC-57553 (e-PCR)
- UniSTS:71941

D11S2921 (e-PCR)
- UniSTS:152074

SHGC-74351 (e-PCR)
- UniSTS:24586

RH69132 (e-PCR)
- UniSTS:30736

CDC42_1530 (e-PCR)
- UniSTS:277081

G15855 (e-PCR)
- UniSTS:76175

A009S40 (e-PCR)
- UniSTS:6545

G22163 (e-PCR)
- UniSTS:22680

SHGC-12429 (e-PCR)
- UniSTS:40859

G32824 (e-PCR)
- UniSTS:117403

CDC42 (e-PCR)
- UniSTS:278181

WI-18965 (e-PCR)
- UniSTS:82105

SHGC-74349 (e-PCR)
- UniSTS:58308

UniSTS:224478 (e-PCR)
- UniSTS:224478

G34846 (e-PCR)
- UniSTS:72173

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Cdc42 protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment or maintenance of cell polarity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in modification of synaptic structure	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of filopodium assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in dendritic spine	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cell division control protein 42 homolog

Names: cell division cycle 42 (GTP binding protein, 25kDa)

NP_001267254.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_009448364.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_009448368.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_054536187.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_054536253.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_054536276.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_063668548.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_063668575.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

XP_063668610.1

EC 3.6.5.1

EC 3.6.5.2

EC 3.6.5.3

EC 3.6.5.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001280325.1 → NP_001267254.1 cell division control protein 42 homolog

See identical proteins and their annotated locations for NP_001267254.1

Status: PROVISIONAL

Source sequence(s)

AK306033

UniProtKB/TrEMBL

G2HH19

Related

ENSPTRP00000077648.1, ENSPTRT00000092388.1

Conserved Domains (2) summary

smart00174
Location:6 → 179

RHO; Rho (Ras homology) subfamily of Ras-like small GTPases

cd01874
Location:3 → 177

Cdc42; cell division cycle 42 (Cdc42) is a small GTPase of the Rho family

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

208926162..208987577 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063812540.1 → XP_063668610.1 cell division control protein 42 homolog isoform X3

UniProtKB/TrEMBL

A0A2J8K465, A0A6D2WBV4, H2PY98
XM_054680301.2 → XP_054536276.1 cell division control protein 42 homolog isoform X5
XM_009450093.5 → XP_009448368.1 cell division control protein 42 homolog isoform X2

See identical proteins and their annotated locations for XP_009448368.1

UniProtKB/TrEMBL

A0A2I3TL10, A0A2J8K464, A0A6D2WW87

Related

ENSPTRP00000089608.1

Conserved Domains (1) summary

cd01874
Location:3 → 177

Cdc42; cell division cycle 42 (Cdc42) is a small GTPase of the Rho family
XM_063812505.1 → XP_063668575.1 cell division control protein 42 homolog isoform X3

UniProtKB/TrEMBL

A0A2J8K465, A0A6D2WBV4, H2PY98
XM_063812478.1 → XP_063668548.1 cell division control protein 42 homolog isoform X3

UniProtKB/TrEMBL

A0A2J8K465, A0A6D2WBV4, H2PY98
XM_009450089.5 → XP_009448364.1 cell division control protein 42 homolog isoform X3

See identical proteins and their annotated locations for XP_009448364.1

UniProtKB/TrEMBL

A0A2J8K465, A0A6D2WBV4, H2PY98

Conserved Domains (1) summary

cd01874
Location:3 → 177

Cdc42; cell division cycle 42 (Cdc42) is a small GTPase of the Rho family
XM_054680278.2 → XP_054536253.1 cell division control protein 42 homolog isoform X4
XM_054680212.2 → XP_054536187.1 cell division control protein 42 homolog isoform X1