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UROD uroporphyrinogen decarboxylase [ Pan troglodytes (chimpanzee) ]

Gene ID: 456541, updated on 29-Mar-2024

Summary

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Official Symbol
URODprovided by VGNC
Official Full Name
uroporphyrinogen decarboxylaseprovided by VGNC
Primary source
VGNC:VGNC:1719
Locus tag
CK820_G0025619
See related
Ensembl:ENSPTRG00000000668
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See UROD in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (185948994..185953361, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (45345941..45350308)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene histone-lysine N-methyltransferase SETMAR-like Neighboring gene zinc finger SWIM-type containing 5 Neighboring gene oligosaccharyltransferase complex subunit OSTC-like Neighboring gene HECT domain E3 ubiquitin protein ligase 3 Neighboring gene mitochondrial ribosomal protein S17 pseudogene Neighboring gene peptidyl-prolyl cis-trans isomerase A-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables uroporphyrinogen decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
uroporphyrinogen decarboxylase
XP_009454712.1
XP_009454715.1
XP_009454725.1
XP_063658828.1
XP_513127.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    185948994..185953361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_513127.7 → XP_513127.1  uroporphyrinogen decarboxylase isoform X1

    See identical proteins and their annotated locations for XP_513127.1

    UniProtKB/TrEMBL
    A0A2I3T6D9, A0A2J8LZV8, A0A2J8LZW3, A0A6D2W7Q9, A0A6D2XD78, H2PYW8
    Related
    ENSPTRP00000001156.4
    Conserved Domains (1) summary
    cd00717
    Location:20 → 359
    URO-D; Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction ...

  2. XM_009456437.4 → XP_009454712.1  uroporphyrinogen decarboxylase isoform X2

    See identical proteins and their annotated locations for XP_009454712.1

    Conserved Domains (1) summary
    cd00717
    Location:1 → 324
    URO-D; Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction ...

  3. XM_009456440.4 → XP_009454715.1  uroporphyrinogen decarboxylase isoform X3

    See identical proteins and their annotated locations for XP_009454715.1

    UniProtKB/TrEMBL
    A0A2I3TIA8, A0A2J8LZW4, A0A6D2W3D1
    Related
    ENSPTRP00000088614.1
    Conserved Domains (1) summary
    cd00717
    Location:20 → 313
    URO-D; Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction ...

  4. XM_009456450.5 → XP_009454725.1  uroporphyrinogen decarboxylase isoform X4

    See identical proteins and their annotated locations for XP_009454725.1

    Conserved Domains (1) summary
    cd00717
    Location:17 → 287
    URO-D; Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction ...

  5. XM_063802758.1 → XP_063658828.1  uroporphyrinogen decarboxylase isoform X4

Nucleotide Protein
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