PRDX1 peroxiredoxin 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PRDX1provided by VGNC
Official Full Name: peroxiredoxin 1provided by VGNC
Primary source: VGNC:VGNC:1469
Locus tag: CK820_G0025630
See related: Ensembl:ENSPTRG00000000675
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (185443513..185455362)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (45843940..45855790, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH69651 (e-PCR)
- UniSTS:38457

SHGC-146777 (e-PCR)
- UniSTS:175424

D1S2391 (e-PCR)
- UniSTS:73795

SHGC-132089 (e-PCR)
- UniSTS:170638

G62947 (e-PCR)
- UniSTS:139922

A007G24 (e-PCR)
- UniSTS:72345

RH70158 (e-PCR)
- UniSTS:87496

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables thioredoxin peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell redox homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to stress	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hydrogen peroxide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in leukocyte activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in removal of superoxide radicals	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: peroxiredoxin-1

XP_001156568.1

EC 1.11.1.24

EC 1.11.1.7

XP_003308110.1

EC 1.11.1.24

EC 1.11.1.7

XP_016817283.1

EC 1.11.1.24

EC 1.11.1.7

XP_054538589.1

EC 1.11.1.24

EC 1.11.1.7

XP_054538591.1

EC 1.11.1.24

EC 1.11.1.7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

185443513..185455362

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001156568.8 → XP_001156568.1 peroxiredoxin-1

See identical proteins and their annotated locations for XP_001156568.1

UniProtKB/TrEMBL

A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4

Conserved Domains (1) summary

cd03015
Location:8 → 180

PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
XM_003308062.7 → XP_003308110.1 peroxiredoxin-1

See identical proteins and their annotated locations for XP_003308110.1

UniProtKB/TrEMBL

A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4

Conserved Domains (1) summary

cd03015
Location:8 → 180

PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
XM_054682614.2 → XP_054538589.1 peroxiredoxin-1

UniProtKB/TrEMBL

A0A2J8M026, A0A6D2WW41, H2PYX4
XM_016961794.4 → XP_016817283.1 peroxiredoxin-1

UniProtKB/TrEMBL

A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4

Related

ENSPTRP00000001167.4

Conserved Domains (1) summary

cd03015
Location:8 → 180

PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...
XM_054682616.2 → XP_054538591.1 peroxiredoxin-1

UniProtKB/TrEMBL

A0A2J8M026, A0A6D2WW41, H2PYX4