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ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit [ Pan troglodytes (chimpanzee) ]

Gene ID: 456124, updated on 3-Apr-2024

Summary

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Official Symbol
ERCC2provided by VGNC
Official Full Name
ERCC excision repair 2, TFIIH core complex helicase subunitprovided by VGNC
Primary source
VGNC:VGNC:7479
Locus tag
CK820_G0049438
See related
Ensembl:ENSPTRG00000011149
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (48309704..48328738, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (48307975..48328784, complement)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein uS9-like Neighboring gene kinesin light chain 3 Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene RNA polymerase I subunit G Neighboring gene ERCC excision repair 1, endonuclease non-catalytic subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mitotic recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
general transcription and DNA repair factor IIH helicase subunit XPD
Names
TFIIH basal transcription factor complex helicase subunit
excision repair cross-complementation group 2
excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
NP_001233519.1
XP_009434029.1
XP_016789562.1
XP_054528420.1
XP_054528421.1
XP_063656326.1
XP_063656327.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246590.1 → NP_001233519.1  general transcription and DNA repair factor IIH helicase subunit XPD

    See identical proteins and their annotated locations for NP_001233519.1

    Status: PROVISIONAL

    Source sequence(s)
    AK306207
    UniProtKB/TrEMBL
    A0A2J8PYJ3, A0A6D2Y303, G2HHJ3, H2QGL4
    Related
    ENSPTRP00000079029.1, ENSPTRT00000100344.1
    Conserved Domains (1) summary
    TIGR00604
    Location:7 → 708
    rad3; DNA repair helicase (rad3)

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    48309704..48328738 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054672445.2 → XP_054528420.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X4

  2. XM_054672446.2 → XP_054528421.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X5

  3. XM_063800256.1 → XP_063656326.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X3

  4. XM_063800257.1 → XP_063656327.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X6

  5. XM_009435754.5 → XP_009434029.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X2

    See identical proteins and their annotated locations for XP_009434029.1

    UniProtKB/TrEMBL
    A0A2I3T9J7
    Conserved Domains (4) summary
    smart00488
    Location:17 → 263
    DEXDc2; DEAD-like helicases superfamily
    smart00491
    Location:525 → 669
    HELICc2; helicase superfamily c-terminal domain
    TIGR00604
    Location:16 → 691
    rad3; DNA repair helicase (rad3)
    pfam06777
    Location:255 → 396
    HBB; Helical and beta-bridge domain

  6. XM_016934073.4 → XP_016789562.1  general transcription and DNA repair factor IIH helicase subunit XPD isoform X1

    UniProtKB/TrEMBL
    H2QGL4
    Conserved Domains (4) summary
    smart00488
    Location:17 → 289
    DEXDc2; DEAD-like helicases superfamily
    smart00491
    Location:551 → 695
    HELICc2; helicase superfamily c-terminal domain
    TIGR00604
    Location:16 → 717
    rad3; DNA repair helicase (rad3)
    pfam06777
    Location:281 → 422
    HBB; Helical and beta-bridge domain
Nucleotide Protein
Heading Accession and Version

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