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PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 455855, updated on 29-Mar-2024

Summary

Official Symbol
PIK3R2provided by VGNC
Official Full Name
phosphoinositide-3-kinase regulatory subunit 2provided by VGNC
Primary source
VGNC:VGNC:13305
Locus tag
CK820_G0026093
See related
Ensembl:ENSPTRG00000010694
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (20803234..20820601)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (20803272..20820640)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene interleukin 12 receptor subunit beta 1 Neighboring gene uncharacterized LOC134809042 Neighboring gene microtubule associated serine/threonine kinase 3 Neighboring gene IFI30 lysosomal thiol reductase Neighboring gene MPV17 mitochondrial inner membrane protein like 2

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
phosphatidylinositol 3-kinase regulatory subunit beta
Names
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    20803234..20820601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_512509.7XP_512509.2  phosphatidylinositol 3-kinase regulatory subunit beta isoform X1

    See identical proteins and their annotated locations for XP_512509.2

    UniProtKB/TrEMBL
    A0A2I3SPG7, A0A2I3TJS4, A0A2J8LTC8, A0A6D2W4W8, H2QFS6
    Related
    ENSPTRP00000018245.4
    Conserved Domains (5) summary
    cd09930
    Location:615717
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:322432
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11909
    Location:780
    SH3_PI3K_p85beta; Src Homology 3 domain of the p85beta regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12926
    Location:437597
    iSH2_PIK3R2; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 2, PIK3R2, also called p85beta
    cd04388
    Location:110296
    RhoGAP_p85; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region protein) ...
  2. XM_063800614.1XP_063656684.1  phosphatidylinositol 3-kinase regulatory subunit beta isoform X2