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LPIN2 lipin 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 455317, updated on 3-Apr-2024

Summary

Official Symbol
LPIN2provided by VGNC
Official Full Name
lipin 2provided by VGNC
Primary source
VGNC:VGNC:5180
Locus tag
CK820_G0018494
See related
Ensembl:ENSPTRG00000009833
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See LPIN2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 17 NC_072415.2 (27884063..27987289)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 18 NC_072416.1 (26807403..26910533)

Chromosome 17 - NC_072415.2Genomic Context describing neighboring genes Neighboring gene myomesin 1 Neighboring gene U7 small nuclear RNA Neighboring gene small nucleolar RNA SNORA70 Neighboring gene uncharacterized LOC104003125 Neighboring gene cysteine and histidine-rich domain-containing protein 1-like Neighboring gene elastin microfibril interfacer 2 Neighboring gene uncharacterized LOC134808636 Neighboring gene small nucleolar RNA U13 Neighboring gene structural maintenance of chromosomes flexible hinge domain containing 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in fatty acid catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in triglyceride biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphatidate phosphatase LPIN2
XP_009432027.1
XP_016788888.1
XP_016788889.1
XP_016788890.1
XP_016788891.1
XP_063651605.1
XP_063651606.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072415.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    27884063..27987289
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016933402.4XP_016788891.1  phosphatidate phosphatase LPIN2 isoform X4

    UniProtKB/TrEMBL
    A0A2J8MP67, A0A6D2XST3, H2QE76
    Conserved Domains (4) summary
    pfam04571
    Location:1107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:637862
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:875893
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:469560
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
  2. XM_016933401.4XP_016788890.1  phosphatidate phosphatase LPIN2 isoform X4

    UniProtKB/TrEMBL
    A0A2J8MP67, A0A6D2XST3, H2QE76
    Related
    ENSPTRP00000016737.2
    Conserved Domains (4) summary
    pfam04571
    Location:1107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:637862
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam15017
    Location:875893
    WRNPLPNID; Putative WW-binding domain and destruction box
    pfam16876
    Location:469560
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
  3. XM_063795535.1XP_063651605.1  phosphatidate phosphatase LPIN2 isoform X4

    UniProtKB/TrEMBL
    A0A2J8MP67, A0A6D2XST3, H2QE76
  4. XM_063795536.1XP_063651606.1  phosphatidate phosphatase LPIN2 isoform X5

  5. XM_016933400.4XP_016788889.1  phosphatidate phosphatase LPIN2 isoform X3

  6. XM_009433752.5XP_009432027.1  phosphatidate phosphatase LPIN2 isoform X1

    See identical proteins and their annotated locations for XP_009432027.1

    Conserved Domains (4) summary
    pfam15017
    Location:913932
    AF1Q; Drug resistance and apoptosis regulator
    pfam04571
    Location:38143
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:674899
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:506596
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain
  7. XM_016933399.4XP_016788888.1  phosphatidate phosphatase LPIN2 isoform X2

RNA

  1. XR_008540709.2 RNA Sequence