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CLTC clathrin heavy chain [ Pan troglodytes (chimpanzee) ]

Gene ID: 455168, updated on 29-Mar-2024

Summary

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Official Symbol
CLTCprovided by VGNC
Official Full Name
clathrin heavy chainprovided by VGNC
Primary source
VGNC:VGNC:9237
Locus tag
CK820_G0020843
See related
Ensembl:ENSPTRG00000009472
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (72738504..72813963)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (70920876..70998758)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene DEAH-box helicase 40 Neighboring gene peptidyl-tRNA hydrolase 2 Neighboring gene vacuole membrane protein 1 Neighboring gene microRNA mir-21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables clathrin light chain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of clathrin coat of coated pit IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of clathrin coat of trans-Golgi network vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of clathrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in clathrin-coated endocytic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular exosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
clathrin heavy chain 1
Names
clathrin, heavy chain (Hc)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    72738504..72813963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001136053.7 → XP_001136053.1  clathrin heavy chain 1 isoform X2

    See identical proteins and their annotated locations for XP_001136053.1

    UniProtKB/TrEMBL
    A0A2J8MEY0, A0A2J8MEY4, A0A6D2X581, H2QZP7
    Related
    ENSPTRP00000039324.3
    Conserved Domains (6) summary
    smart00299
    Location:1274 → 1416
    CLH; Clathrin heavy chain repeat homology
    sd00006
    Location:1105 → 1131
    TPR; TPR repeat [structural motif]
    pfam00637
    Location:979 → 1119
    Clathrin; Region in Clathrin and VPS
    pfam01394
    Location:198 → 234
    Clathrin_propel; Clathrin propeller repeat
    pfam09268
    Location:331 → 354
    Clathrin-link; Clathrin, heavy-chain linker
    pfam13838
    Location:356 → 421
    Clathrin_H_link; Clathrin-H-link

  2. XM_009432958.4 → XP_009431233.1  clathrin heavy chain 1 isoform X1

    See identical proteins and their annotated locations for XP_009431233.1

    UniProtKB/TrEMBL
    A0A2J8MEY4, K7CCE3
    Related
    ENSPTRP00000093953.1
    Conserved Domains (6) summary
    smart00299
    Location:1274 → 1416
    CLH; Clathrin heavy chain repeat homology
    sd00006
    Location:1105 → 1131
    TPR; TPR repeat [structural motif]
    pfam00637
    Location:979 → 1119
    Clathrin; Region in Clathrin and VPS
    pfam01394
    Location:198 → 234
    Clathrin_propel; Clathrin propeller repeat
    pfam09268
    Location:331 → 354
    Clathrin-link; Clathrin, heavy-chain linker
    pfam13838
    Location:356 → 421
    Clathrin_H_link; Clathrin-H-link
Nucleotide Protein
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