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ITGA2B integrin subunit alpha 2b [ Pan troglodytes (chimpanzee) ]

Gene ID: 454730, updated on 3-Apr-2024

Summary

Official Symbol
ITGA2Bprovided by VGNC
Official Full Name
integrin subunit alpha 2bprovided by VGNC
Primary source
VGNC:VGNC:9336
Locus tag
CK820_G0050754
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (23511288..23530071)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (21745407..21770323)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene frizzled class receptor 2 Neighboring gene G-patch domain containing 8 Neighboring gene ribosomal protein uL30-like Neighboring gene family with sequence similarity 171 member A2

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
integrin alpha-IIb
Names
integrin alpha 2b
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    23511288..23530071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024350246.3XP_024206014.1  integrin alpha-IIb isoform X2

    UniProtKB/TrEMBL
    A0A2J8J4M3
    Conserved Domains (2) summary
    smart00191
    Location:453507
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:550990
    Integrin_alpha2; Integrin alpha
  2. XM_024350245.3XP_024206013.1  integrin alpha-IIb isoform X1

    UniProtKB/TrEMBL
    A0A2J8J4M3
    Conserved Domains (3) summary
    smart00191
    Location:453507
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:10891103
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:550990
    Integrin_alpha2; Integrin alpha
  3. XM_024350248.3XP_024206016.1  integrin alpha-IIb isoform X4

    UniProtKB/TrEMBL
    A0A2J8J4M3
    Conserved Domains (2) summary
    smart00191
    Location:453507
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:550990
    Integrin_alpha2; Integrin alpha
  4. XM_054671395.2XP_054527370.1  integrin alpha-IIb isoform X3