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STAT5B signal transducer and activator of transcription 5B [ Pan troglodytes (chimpanzee) ]

Gene ID: 454679, updated on 11-Apr-2024

Summary

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Official Symbol
STAT5Bprovided by VGNC
Official Full Name
signal transducer and activator of transcription 5Bprovided by VGNC
Primary source
VGNC:VGNC:12700
Locus tag
CK820_G0038992
See related
Ensembl:ENSPTRG00000009198
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
STAT5A
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Genomic context

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See STAT5B in Genome Data Viewer
Location:
chromosome: 17
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (25856571..25944739)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (24041221..24129200)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 3 Neighboring gene signal transducer and activator of transcription 5A Neighboring gene GH3 domain containing Neighboring gene hypocretin neuropeptide precursor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5B
Names
signal transducer and activator of transcription 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    25856571..25944739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024350299.3 → XP_024206067.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KFW3, K7C9E4
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_024350300.3 → XP_024206068.1  signal transducer and activator of transcription 5B isoform X2

    UniProtKB/TrEMBL
    K7C9E4
    Conserved Domains (4) summary
    cd10420
    Location:522 → 666
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:88 → 279
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:281 → 438
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:5 → 73
    STAT_int; STAT protein, protein interaction domain

  3. XM_024350296.3 → XP_024206064.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KFW3, K7C9E4
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  4. XM_063798574.1 → XP_063654644.1  signal transducer and activator of transcription 5B isoform X2

  5. XM_024350298.3 → XP_024206066.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KFW3, K7C9E4
    Conserved Domains (4) summary
    cd10420
    Location:573 → 717
    SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain

  6. XM_054670880.2 → XP_054526855.1  signal transducer and activator of transcription 5B isoform X2

Nucleotide Protein
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