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GRAP GRB2 related adaptor protein [ Pan troglodytes (chimpanzee) ]

Gene ID: 454496, updated on 3-Apr-2024

Summary

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Gene symbol
GRAP
Gene description
GRB2 related adaptor protein
Locus tag
CK820_G0050194
See related
Ensembl:ENSPTRG00000047873
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
GRAPL
Orthologs
human all
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Genomic context

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Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (51643114..51683745, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (49827571..49857909, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA MBII-202 Neighboring gene solute carrier family 5 member 10 Neighboring gene family with sequence similarity 83 member G Neighboring gene uncharacterized LOC134808956 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC134808957 Neighboring gene kynureninase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables epidermal growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GRB2-related adapter protein
Names
GRB2 related adaptor protein like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    51643114..51683745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024350419.3 → XP_024206187.1  GRB2-related adapter protein

    UniProtKB/TrEMBL
    A0A2J8J714
    Conserved Domains (3) summary
    cd09941
    Location:56 → 150
    SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
    cd11948
    Location:2 → 55
    SH3_GRAP_N; N-terminal Src homology 3 domain of GRB2-related adaptor protein
    cd11951
    Location:162 → 214
    SH3_GRAP_C; C-terminal Src homology 3 domain of GRB2-related adaptor protein

  2. XM_063799724.1 → XP_063655794.1  GRB2-related adapter protein

    UniProtKB/TrEMBL
    A0A2J8J714

  3. XM_063799725.1 → XP_063655795.1  GRB2-related adapter protein

    UniProtKB/TrEMBL
    A0A2J8J714
Nucleotide Protein
Heading Accession and Version

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