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SREBF1 sterol regulatory element binding transcription factor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 454480, updated on 3-Apr-2024

Summary

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Official Symbol
SREBF1provided by VGNC
Official Full Name
sterol regulatory element binding transcription factor 1provided by VGNC
Primary source
VGNC:VGNC:57958
Locus tag
CK820_G0051094
See related
Ensembl:ENSPTRG00000052349
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (49972682..49998453)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (48157158..48182910)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene membrane protein BRI3-like Neighboring gene dynein regulatory complex subunit 3 Neighboring gene target of myb1 like 2 membrane trafficking protein Neighboring gene uncharacterized LOC129137693 Neighboring gene microRNA mir-33b Neighboring gene retinoic acid induced 1 Neighboring gene uncharacterized LOC107969238

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol regulatory element-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    49972682..49998453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054671007.2 → XP_054526982.1  sterol regulatory element-binding protein 1 isoform X1

  2. XM_016932328.4 → XP_016787817.1  sterol regulatory element-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SGI9, A0A2J8J362, A0A6D2W7M4, K7CIC8
    Related
    ENSPTRP00000083569.1
    Conserved Domains (3) summary
    cd00083
    Location:321 → 378
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl25496
    Location:56 → 320
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cl26464
    Location:87 → 210
    Atrophin-1; Atrophin-1 family

  3. XM_054671008.2 → XP_054526983.1  sterol regulatory element-binding protein 1 isoform X4

  4. XM_054671009.2 → XP_054526984.1  sterol regulatory element-binding protein 1 isoform X5

  5. XM_063799694.1 → XP_063655764.1  sterol regulatory element-binding protein 1 isoform X3

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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