POLR2A RNA polymerase II subunit A [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: POLR2Aprovided by VGNC
Official Full Name: RNA polymerase II subunit Aprovided by VGNC
Primary source: VGNC:VGNC:48945
Locus tag: CK820_G0036797
See related: Ensembl:ENSPTRG00000008691
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	19	NC_072417.2 (17996807..18027266)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	17	NC_072415.1 (16236387..16266762)

Chromosome 19 - NC_072417.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH80168 (e-PCR)
- UniSTS:91921

WI-1288 (e-PCR)
- UniSTS:39990

WI-16243 (e-PCR)
- UniSTS:7743

G43606 (e-PCR)
- UniSTS:95041

RH104382 (e-PCR)
- UniSTS:98707

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase II, core complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA-directed RNA polymerase II subunit RPB1

Names: polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A

XP_016786944.1

EC 2.7.7.48

EC 2.7.7.6

XP_024205979.1

EC 2.7.7.48

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

17996807..18027266

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016931455.4 → XP_016786944.1 DNA-directed RNA polymerase II subunit RPB1 isoform X1

UniProtKB/TrEMBL

H2R1J6

Related

ENSPTRP00000067657.1

Conserved Domains (5) summary

cd02584
Location:1058 → 1476

RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain

smart01104
Location:1491 → 1610

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

cd02733
Location:19 → 876

RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain

pfam05109
Location:1854 → 1959

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

pfam04992
Location:896 → 1079

RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6
XM_024350211.3 → XP_024205979.1 DNA-directed RNA polymerase II subunit RPB1 isoform X2

Conserved Domains (5) summary

cd02584
Location:1025 → 1443

RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain

smart01104
Location:1458 → 1577

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

cd02733
Location:1 → 843

RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain

pfam05109
Location:1821 → 1926

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

pfam04992
Location:863 → 1046

RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6