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ITGAX integrin subunit alpha X [ Pan troglodytes (chimpanzee) ]

Gene ID: 454070, updated on 3-Apr-2024

Summary

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Official Symbol
ITGAXprovided by VGNC
Official Full Name
integrin subunit alpha Xprovided by VGNC
Primary source
VGNC:VGNC:5827
Locus tag
CK820_G0050590
See related
Ensembl:ENSPTRG00000008043
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See ITGAX in Genome Data Viewer
Location:
chromosome: 16
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (35382537..35412745)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (35382438..35412641)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 72 Neighboring gene pyrin domain containing 1 Neighboring gene integrin subunit alpha M Neighboring gene integrin subunit alpha D Neighboring gene cytochrome c oxidase subunit 6A2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-X
Names
integrin alpha X
integrin, alpha X (complement component 3 receptor 4 subunit)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    35382537..35412745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016929753.3 → XP_016785242.1  integrin alpha-X isoform X1

    UniProtKB/TrEMBL
    A0A2I3SQH8, A0A2J8J560, A0A2J8J575, A0A6D2VSQ0, A0A6D2XS61, K7A9I9
    Related
    ENSPTRP00000063615.1
    Conserved Domains (4) summary
    smart00191
    Location:454 → 504
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:150 → 325
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam00357
    Location:1129 → 1143
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:615 → 1032
    Integrin_alpha2; Integrin alpha

  2. XM_054668339.2 → XP_054524314.1  integrin alpha-X isoform X2

  3. XM_054668340.2 → XP_054524315.1  integrin alpha-X isoform X3

RNA

  1. XR_010152585.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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