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STUB1 STIP1 homology and U-box containing protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 453803, updated on 29-Mar-2024

Summary

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Official Symbol
STUB1provided by VGNC
Official Full Name
STIP1 homology and U-box containing protein 1provided by VGNC
Primary source
VGNC:VGNC:9146
Locus tag
CK820_G0049947
See related
Ensembl:ENSPTRG00000007553
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (3039609..3042304)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (3039982..3042305)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene rhomboid like 1 Neighboring gene uncharacterized LOC107968684 Neighboring gene jumonji domain containing 8 Neighboring gene WD repeat domain 24 Neighboring gene F-box and leucine rich repeat protein 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to misfolded protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CHIP
Names
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
XP_009428299.1
XP_009428300.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    3039609..3042304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009430025.5 → XP_009428300.1  E3 ubiquitin-protein ligase CHIP isoform X2

    See identical proteins and their annotated locations for XP_009428300.1

    UniProtKB/TrEMBL
    A0A2J8J8C8, A0A6D2XF45, H2QA80
    Related
    ENSPTRP00000012898.2
    Conserved Domains (4) summary
    PLN03088
    Location:26 → 126
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:26 → 54
    TPR; TPR repeat [structural motif]
    cd16654
    Location:227 → 293
    RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
    pfam18391
    Location:142 → 225
    CHIP_TPR_N; CHIP N-terminal tetratricopeptide repeat domain

  2. XM_009430024.5 → XP_009428299.1  E3 ubiquitin-protein ligase CHIP isoform X1

    See identical proteins and their annotated locations for XP_009428299.1

    UniProtKB/TrEMBL
    A0A2J8J8D1
    Conserved Domains (3) summary
    sd00006
    Location:26 → 54
    TPR; TPR repeat [structural motif]
    cd16654
    Location:227 → 320
    RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
    cl26005
    Location:26 → 126
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
Nucleotide Protein
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