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SIN3A SIN3 transcription regulator family member A [ Pan troglodytes (chimpanzee) ]

Gene ID: 453759, updated on 3-Apr-2024

Summary

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Official Symbol
SIN3Aprovided by VGNC
Official Full Name
SIN3 transcription regulator family member Aprovided by VGNC
Primary source
VGNC:VGNC:1878
Locus tag
CK820_G0036650
See related
Ensembl:ENSPTRG00000007300
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (67306832..67391398, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (67280139..67366248, complement)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134808460 Neighboring gene nei like DNA glycosylase 1 Neighboring gene microRNA mir-631 Neighboring gene mannosidase alpha class 2C member 1 Neighboring gene large ribosomal subunit protein eL13-like Neighboring gene protein tyrosine phosphatase non-receptor type 9 Neighboring gene small nuclear ribonucleoprotein F-like Neighboring gene snurportin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Sin3-type complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
paired amphipathic helix protein Sin3a
Names
SIN3 homolog A, transcription regulator
SIN3 transcription regulator homolog A
transcriptional co-repressor Sin3A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    67306832..67391398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016927208.4 → XP_016782697.1  paired amphipathic helix protein Sin3a isoform X1

    UniProtKB/TrEMBL
    A0A2I3S233

  2. XM_063794216.1 → XP_063650286.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  3. XM_063794217.1 → XP_063650287.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  4. XM_009429558.5 → XP_009427833.1  paired amphipathic helix protein Sin3a isoform X2

    See identical proteins and their annotated locations for XP_009427833.1

    UniProtKB/TrEMBL
    A0A2I3S233, A0A2J8KS85, A0A6D2XU66, H2R491
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1213
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  5. XM_063794212.1 → XP_063650282.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  6. XM_063794218.1 → XP_063650288.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  7. XM_063794210.1 → XP_063650280.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  8. XM_009429559.5 → XP_009427834.1  paired amphipathic helix protein Sin3a isoform X2

    See identical proteins and their annotated locations for XP_009427834.1

    UniProtKB/TrEMBL
    A0A2I3S233, A0A2J8KS85, A0A6D2XU66, H2R491
    Related
    ENSPTRP00000070896.1
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1213
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  9. XM_016927209.4 → XP_016782698.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2I3S233, A0A2J8KS85, A0A6D2XU66, H2R491
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1213
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  10. XM_063794220.1 → XP_063650290.1  paired amphipathic helix protein Sin3a isoform X4

  11. XM_063794211.1 → XP_063650281.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  12. XM_063794214.1 → XP_063650284.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  13. XM_001142716.8 → XP_001142716.1  paired amphipathic helix protein Sin3a isoform X2

    See identical proteins and their annotated locations for XP_001142716.1

    UniProtKB/TrEMBL
    A0A2I3S233, A0A2J8KS85, A0A6D2XU66, H2R491
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1213
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  14. XM_063794219.1 → XP_063650289.1  paired amphipathic helix protein Sin3a isoform X3

  15. XM_063794213.1 → XP_063650283.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491

  16. XM_063794215.1 → XP_063650285.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    A0A2J8KS85, A0A6D2XU66, H2R491
Nucleotide Protein
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