IGF1R insulin like growth factor 1 receptor [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: IGF1Rprovided by VGNC
Official Full Name: insulin like growth factor 1 receptorprovided by VGNC
Primary source: VGNC:VGNC:11907
Locus tag: CK820_G0031936
See related: Ensembl:ENSPTRG00000007489
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	16	NC_072414.2 (90467150..90781823)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	15	NC_072413.1 (90441886..90756559)

Chromosome 16 - NC_072414.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Igf1r (e-PCR), detects polymorphism
- UniSTS:526083

G17859 (e-PCR)
- UniSTS:38660

RH94360 (e-PCR)
- UniSTS:85767

WI-20575 (e-PCR)
- UniSTS:8231

SHGC-81342 (e-PCR)
- UniSTS:102703

IGF1R (e-PCR)
- UniSTS:503091

SHGC-34685 (e-PCR)
- UniSTS:28217

AFMa305ye1 (e-PCR)
- UniSTS:50489

SHGC-148975 (e-PCR)
- UniSTS:176714

RH15697 (e-PCR)
- UniSTS:60244

RH94329 (e-PCR)
- UniSTS:87391

RH92510 (e-PCR)
- UniSTS:84085

SHGC-156036 (e-PCR)
- UniSTS:182917

RH120174 (e-PCR)
- UniSTS:132240

GDB:187366 (e-PCR)
- UniSTS:155545

STS-T85175 (e-PCR)
- UniSTS:71083

SHGC-58525 (e-PCR)
- UniSTS:94380

RH44703 (e-PCR)
- UniSTS:78510

WI-21793 (e-PCR)
- UniSTS:22208

RH69514 (e-PCR)
- UniSTS:16327

RH48245 (e-PCR)
- UniSTS:34510

D15S906 (e-PCR)
- UniSTS:71889

RH76769 (e-PCR)
- UniSTS:88021

FAH (e-PCR)
- UniSTS:479963

RH121492 (e-PCR)
- UniSTS:134620

RH77818 (e-PCR)
- UniSTS:74462

RH70207 (e-PCR)
- UniSTS:77278

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin receptor substrate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphatidylinositol 3-kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to glucose stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in insulin-like growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of JNK cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
part_of insulin receptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: insulin-like growth factor 1 receptor

XP_016782981.1

EC 2.7.10.1

XP_016782982.1

EC 2.7.10.1

XP_016782983.1

EC 2.7.10.1

XP_016782984.1

EC 2.7.10.1

XP_054523143.1

EC 2.7.10.1

XP_054523144.1

EC 2.7.10.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

90467150..90781823

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016927492.3 → XP_016782981.1 insulin-like growth factor 1 receptor isoform X1

UniProtKB/TrEMBL

A0A2I3SK97, A0A2J8L7C4, A0A6D2WGH0, H2QA49

Related

ENSPTRP00000012792.4

Conserved Domains (4) summary

cd05032
Location:992 → 1268

PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases

cd00063
Location:835 → 924

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00757
Location:175 → 330

Furin-like; Furin-like cysteine rich region

pfam01030
Location:352 → 466

Recep_L_domain; Receptor L domain
XM_016927495.3 → XP_016782984.1 insulin-like growth factor 1 receptor isoform X2

UniProtKB/TrEMBL

A0A2I3SK97, A0A2J8L7F3

Conserved Domains (4) summary

cd05032
Location:991 → 1267

PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases

cd00063
Location:835 → 924

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00757
Location:175 → 330

Furin-like; Furin-like cysteine rich region

pfam01030
Location:352 → 466

Recep_L_domain; Receptor L domain
XM_016927493.4 → XP_016782982.1 insulin-like growth factor 1 receptor isoform X1

UniProtKB/TrEMBL

A0A2I3SK97, A0A2J8L7C4, A0A6D2WGH0, H2QA49

Conserved Domains (4) summary

cd05032
Location:992 → 1268

PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases

cd00063
Location:835 → 924

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00757
Location:175 → 330

Furin-like; Furin-like cysteine rich region

pfam01030
Location:352 → 466

Recep_L_domain; Receptor L domain
XM_016927494.4 → XP_016782983.1 insulin-like growth factor 1 receptor isoform X1

UniProtKB/TrEMBL

A0A2I3SK97, A0A2J8L7C4, A0A6D2WGH0, H2QA49

Related

ENSPTRP00000076903.1

Conserved Domains (4) summary

cd05032
Location:992 → 1268

PTKc_InsR_like; Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases

cd00063
Location:835 → 924

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00757
Location:175 → 330

Furin-like; Furin-like cysteine rich region

pfam01030
Location:352 → 466

Recep_L_domain; Receptor L domain
XM_054667168.2 → XP_054523143.1 insulin-like growth factor 1 receptor isoform X2

UniProtKB/TrEMBL

A0A2J8L7F3
XM_054667169.2 → XP_054523144.1 insulin-like growth factor 1 receptor isoform X2

UniProtKB/TrEMBL

A0A2J8L7F3