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UBE3A ubiquitin protein ligase E3A [ Pan troglodytes (chimpanzee) ]

Gene ID: 453269, updated on 3-Apr-2024

Summary

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Official Symbol
UBE3Aprovided by VGNC
Official Full Name
ubiquitin protein ligase E3Aprovided by VGNC
Primary source
VGNC:VGNC:1583
Locus tag
CK820_G0037640
See related
Ensembl:ENSPTRG00000006829
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (10088547..10190114)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (10086927..10187975)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 10A (putative) Neighboring gene uncharacterized LOC112205570 Neighboring gene uncharacterized LOC129137185 Neighboring gene small nucleolar RNA SNORD109A Neighboring gene small nucleolar RNA SNORD115

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin-protein ligase E3A
Names
ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
XP_016783262.1
XP_016783272.1
XP_016783273.1
XP_016783274.1
XP_016783275.1
XP_054523251.1
XP_054523252.1
XP_054523254.1
XP_054523255.1
XP_054523256.1
XP_054523258.1
XP_054523259.1
XP_054523261.1
XP_063650521.1
XP_063650522.1
XP_063650523.1
XP_063650524.1
XP_063650525.1
XP_063650526.1
XP_063650527.1
XP_063650528.1
XP_063650529.1
XP_063650531.1
XP_063650532.1
XP_063650533.1
XP_063650534.1
XP_063650535.1
XP_063650536.1
XP_063650537.1
XP_063650538.1
XP_063650539.1
XP_063650540.1
XP_063650541.1
XP_063650542.1
XP_063650543.1
XP_063650544.1
XP_063650545.1
XP_063650546.1
XP_063650547.1
XP_063650548.1
XP_063650549.1
XP_063650550.1
XP_063650551.1
XP_063650552.1
XP_063650553.1
XP_063650554.1
XP_063650555.1
XP_063650556.1
XP_063650557.1
XP_063650558.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    10088547..10190114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063794454.1 → XP_063650524.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  2. XM_016927785.4 → XP_016783274.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2I3SLP4, A0A2J8KLH5, A0A6D2VT55, H2Q918
    Conserved Domains (2) summary
    cd00078
    Location:500 → 850
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam16558
    Location:6 → 60
    AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A

  3. XM_016927786.4 → XP_016783275.1  ubiquitin-protein ligase E3A isoform X4

    UniProtKB/TrEMBL
    A0A2I3SLP4, A0A2I3TGK5
    Related
    ENSPTRP00000088371.1
    Conserved Domains (1) summary
    cd00078
    Location:461 → 811
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

  4. XM_063794453.1 → XP_063650523.1  ubiquitin-protein ligase E3A isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJZ1, A0A2J8KLK5, A0A6D2Y4M9

  5. XM_063794482.1 → XP_063650552.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  6. XM_063794462.1 → XP_063650532.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  7. XM_063794455.1 → XP_063650525.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  8. XM_063794461.1 → XP_063650531.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  9. XM_063794477.1 → XP_063650547.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  10. XM_063794459.1 → XP_063650529.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  11. XM_063794464.1 → XP_063650534.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  12. XM_063794471.1 → XP_063650541.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  13. XM_063794484.1 → XP_063650554.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  14. XM_016927773.4 → XP_016783262.1  ubiquitin-protein ligase E3A isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJZ1, A0A2I3SLP4, A0A2J8KLK5, A0A6D2Y4M9
    Related
    ENSPTRP00000077303.1
    Conserved Domains (2) summary
    cd00078
    Location:523 → 873
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam16558
    Location:29 → 83
    AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A

  15. XM_063794465.1 → XP_063650535.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  16. XM_063794483.1 → XP_063650553.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  17. XM_063794485.1 → XP_063650555.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  18. XM_016927783.4 → XP_016783272.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2I3SLP4, A0A2J8KLH5, A0A6D2VT55, H2Q918
    Conserved Domains (2) summary
    cd00078
    Location:500 → 850
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam16558
    Location:6 → 60
    AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A

  19. XM_016927784.4 → XP_016783273.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2I3SLP4, A0A2J8KLH5, A0A6D2VT55, H2Q918
    Conserved Domains (2) summary
    cd00078
    Location:500 → 850
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam16558
    Location:6 → 60
    AZUL; Amino-terminal Zinc-binding domain of ubiquitin ligase E3A

  20. XM_063794458.1 → XP_063650528.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  21. XM_063794470.1 → XP_063650540.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  22. XM_063794488.1 → XP_063650558.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  23. XM_063794480.1 → XP_063650550.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  24. XM_063794473.1 → XP_063650543.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  25. XM_063794463.1 → XP_063650533.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  26. XM_054667280.1 → XP_054523255.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  27. XM_054667281.1 → XP_054523256.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  28. XM_063794476.1 → XP_063650546.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  29. XM_054667277.1 → XP_054523252.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  30. XM_063794478.1 → XP_063650548.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  31. XM_063794487.1 → XP_063650557.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  32. XM_054667283.1 → XP_054523258.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  33. XM_054667286.1 → XP_054523261.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  34. XM_063794472.1 → XP_063650542.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  35. XM_063794457.1 → XP_063650527.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  36. XM_063794456.1 → XP_063650526.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  37. XM_063794452.1 → XP_063650522.1  ubiquitin-protein ligase E3A isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJZ1, A0A2J8KLK5, A0A6D2Y4M9

  38. XM_063794451.1 → XP_063650521.1  ubiquitin-protein ligase E3A isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJZ1, A0A2J8KLK5, A0A6D2Y4M9

  39. XM_063794481.1 → XP_063650551.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  40. XM_063794475.1 → XP_063650545.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  41. XM_063794479.1 → XP_063650549.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  42. XM_063794474.1 → XP_063650544.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  43. XM_063794469.1 → XP_063650539.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  44. XM_063794466.1 → XP_063650536.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  45. XM_054667276.1 → XP_054523251.1  ubiquitin-protein ligase E3A isoform X1

    UniProtKB/TrEMBL
    A0A2I3SJZ1, A0A2J8KLK5, A0A6D2Y4M9

  46. XM_063794468.1 → XP_063650538.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  47. XM_063794486.1 → XP_063650556.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  48. XM_054667279.1 → XP_054523254.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7

  49. XM_063794467.1 → XP_063650537.1  ubiquitin-protein ligase E3A isoform X3

    UniProtKB/TrEMBL
    A0A2J8KLH5, A0A6D2VT55, H2Q918

  50. XM_054667284.1 → XP_054523259.1  ubiquitin-protein ligase E3A isoform X2

    UniProtKB/TrEMBL
    A0A2J8KLG3, A0A6D2WHU6, K7APY7
Nucleotide Protein
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