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ESR2 estrogen receptor 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452964, updated on 29-Mar-2024

Summary

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Official Symbol
ESR2provided by VGNC
Official Full Name
estrogen receptor 2provided by VGNC
Primary source
VGNC:VGNC:9049
Locus tag
CK820_G0002653
See related
Ensembl:ENSPTRG00000006432
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 15 NC_072413.2 (62206559..62273728, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 14 NC_072412.1 (55473851..55529708, complement)

Chromosome 15 - NC_072413.2Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2 subunit 2-like Neighboring gene sphingosine-1-phosphate phosphatase 1 Neighboring gene spectrin repeat containing nuclear envelope protein 2 Neighboring gene microRNA mir-548h Neighboring gene uncharacterized LOC107968183 Neighboring gene methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Neighboring gene zinc finger and BTB domain containing 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to estrogen stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
estrogen receptor beta
Names
estrogen receptor 2 (ER beta)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    62206559..62273728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024348749.3 → XP_024204517.1  estrogen receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3SG36, A0A2J8PIA6, A0A2J8PIB9, A0A6D2XPD2
    Conserved Domains (3) summary
    cd06949
    Location:263 → 489
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:144 → 225
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:16 → 122
    ERbeta_N; Estrogen receptor beta

  2. XM_024348748.3 → XP_024204516.1  estrogen receptor beta isoform X1

    UniProtKB/TrEMBL
    A0A2I3TGF6, A0A2J8PID8, A0A6D2VYH4, H2Q8G2
    Conserved Domains (3) summary
    cd06949
    Location:263 → 498
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:144 → 225
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:16 → 122
    ERbeta_N; Estrogen receptor beta
Nucleotide Protein
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