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RB1 RB transcriptional corepressor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452715, updated on 3-Apr-2024

Summary

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Official Symbol
RB1provided by VGNC
Official Full Name
RB transcriptional corepressor 1provided by VGNC
Primary source
VGNC:VGNC:14463
Locus tag
CK820_G0031644
See related
Ensembl:ENSPTRG00000005864
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 14 NC_072412.2 (53902648..54073523)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 13 NC_072411.1 (49269565..49440304)

Chromosome 14 - NC_072412.2Genomic Context describing neighboring genes Neighboring gene integral membrane protein 2B Neighboring gene uncharacterized LOC101056985 Neighboring gene protein phosphatase 1 regulatory subunit 26-like Neighboring gene PEST proteolytic signal-containing nuclear protein-like Neighboring gene lysophosphatidic acid receptor 6 Neighboring gene uncharacterized LOC129136728 Neighboring gene RCC1 and BTB domain containing protein 2 Neighboring gene uncharacterized LOC129136729

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mapping the homolog of the human Rb1 gene to chromosome 14 of higher primates. Verma RS, et al. Mamm Genome, 1996 Aug. PMID 8678979

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis involved in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Rb-E2F complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinoblastoma-associated protein
Names
retinoblastoma 1 (including osteosarcoma)
retinoblastoma protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    53902648..54073523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_509777.6 → XP_509777.3  retinoblastoma-associated protein isoform X1

    See identical proteins and their annotated locations for XP_509777.3

    UniProtKB/TrEMBL
    A0A2I3T1W1, A0A2J8L8V8, A0A6D2Y5T6, H2Q7K0
    Related
    ENSPTRP00000009974.4
    Conserved Domains (4) summary
    pfam01857
    Location:646 → 763
    RB_B; Retinoblastoma-associated protein B domain
    pfam01858
    Location:373 → 573
    RB_A; Retinoblastoma-associated protein A domain
    pfam08934
    Location:768 → 924
    Rb_C; Rb C-terminal domain
    pfam11934
    Location:114 → 225
    DUF3452; Domain of unknown function (DUF3452)

  2. XM_063792510.1 → XP_063648580.1  retinoblastoma-associated protein isoform X4

  3. XM_063792514.1 → XP_063648584.1  retinoblastoma-associated protein isoform X5

  4. XM_054664916.2 → XP_054520891.1  retinoblastoma-associated protein isoform X6

  5. XM_063792508.1 → XP_063648578.1  retinoblastoma-associated protein isoform X3

  6. XM_063792511.1 → XP_063648581.1  retinoblastoma-associated protein isoform X4

  7. XM_063792515.1 → XP_063648585.1  retinoblastoma-associated protein isoform X5

  8. XM_016925689.3 → XP_016781178.1  retinoblastoma-associated protein isoform X2

    UniProtKB/TrEMBL
    Q9BDQ3

  9. XM_063792512.1 → XP_063648582.1  retinoblastoma-associated protein isoform X4

  10. XM_063792509.1 → XP_063648579.1  retinoblastoma-associated protein isoform X3

  11. XM_063792513.1 → XP_063648583.1  retinoblastoma-associated protein isoform X4

Nucleotide Protein
Heading Accession and Version

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