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PXN paxillin [ Pan troglodytes (chimpanzee) ]

Gene ID: 452303, updated on 3-Apr-2024

Summary

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Official Symbol
PXNprovided by VGNC
Official Full Name
paxillinprovided by VGNC
Primary source
VGNC:VGNC:5558
Locus tag
CK820_G0021696
See related
Ensembl:ENSPTRG00000005527 Ensembl:ENSPTRG00000046402
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (127011037..127066242, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (125624783..125679961, complement)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene GCN1 activator of EIF2AK4 Neighboring gene uncharacterized LOC104001712 Neighboring gene ribosomal protein lateral stalk subunit P0 Neighboring gene nucleoside diphosphate kinase, mitochondrial Neighboring gene U4 spliceosomal RNA Neighboring gene U4 spliceosomal RNA Neighboring gene sirtuin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in endothelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
paxillin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    127011037..127066242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_509424.8 → XP_509424.3  paxillin isoform X21

    See identical proteins and their annotated locations for XP_509424.3

    UniProtKB/TrEMBL
    A0A2I3S2E1, A0A2J8MDT1, A0A6D2WFN7, H2Q704, K7BZ21
    Related
    ENSPTRP00000009381.7
    Conserved Domains (5) summary
    cd09407
    Location:383 → 434
    LIM2_Paxillin; The second LIM domain of paxillin
    cd09409
    Location:442 → 494
    LIM3_Paxillin; The third LIM domain of paxillin
    cd09411
    Location:501 → 552
    LIM4_Paxillin; The fourth LIM domain of Paxillin
    cd09336
    Location:324 → 376
    LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    pfam03535
    Location:54 → 253
    Paxillin; Paxillin family

  2. XM_063785080.1 → XP_063641150.1  paxillin isoform X15

  3. XM_001159942.7 → XP_001159942.2  paxillin isoform X14

    See identical proteins and their annotated locations for XP_001159942.2

    UniProtKB/TrEMBL
    A0A2I3TB71, A0A2J8MDU4, A0A803KL45, K7BLW6
    Conserved Domains (5) summary
    cd09338
    Location:476 → 528
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09407
    Location:417 → 468
    LIM2_Paxillin; The second LIM domain of paxillin
    cd09411
    Location:535 → 586
    LIM4_Paxillin; The fourth LIM domain of Paxillin
    cd09336
    Location:358 → 410
    LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    pfam03535
    Location:54 → 253
    Paxillin; Paxillin family

  4. XM_054663666.2 → XP_054519641.1  paxillin isoform X10

  5. XM_009426377.5 → XP_009424652.1  paxillin isoform X4

    UniProtKB/TrEMBL
    A0A2I3S2N0, A0A2I3SDP5, A0A2J8MDT7, A0A6D2X9J5
    Related
    ENSPTRP00000075096.1
    Conserved Domains (6) summary
    cd09338
    Location:966 → 1018
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09407
    Location:907 → 958
    LIM2_Paxillin; The second LIM domain of paxillin
    cd09411
    Location:1025 → 1076
    LIM4_Paxillin; The fourth LIM domain of Paxillin
    PHA03247
    Location:314 → 606
    PHA03247; large tegument protein UL36; Provisional
    cd09336
    Location:848 → 900
    LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    pfam03535
    Location:54 → 253
    Paxillin; Paxillin family

  6. XM_054663672.2 → XP_054519647.1  paxillin isoform X24

    UniProtKB/TrEMBL
    A0A2I3S8V3, A0A2J8MDT8, A0A6D2WJ48

  7. XM_063785085.1 → XP_063641155.1  paxillin isoform X19

  8. XM_063785087.1 → XP_063641157.1  paxillin isoform X22

    UniProtKB/TrEMBL
    A0A2I3RLQ8

  9. XM_063785086.1 → XP_063641156.1  paxillin isoform X20

  10. XM_063785082.1 → XP_063641152.1  paxillin isoform X17

  11. XM_063785072.1 → XP_063641142.1  paxillin isoform X6

  12. XM_063785081.1 → XP_063641151.1  paxillin isoform X16

    UniProtKB/TrEMBL
    A0A2I3RB75, A0A2J8MDU8, A0A6D2Y470

  13. XM_054663669.2 → XP_054519644.1  paxillin isoform X13

  14. XM_063785079.1 → XP_063641149.1  paxillin isoform X12

  15. XM_063785078.1 → XP_063641148.1  paxillin isoform X9

  16. XM_063785077.1 → XP_063641147.1  paxillin isoform X8

  17. XM_063785075.1 → XP_063641145.1  paxillin isoform X7

  18. XM_063785071.1 → XP_063641141.1  paxillin isoform X2

  19. XM_063785070.1 → XP_063641140.1  paxillin isoform X1

  20. XM_063785092.1 → XP_063641162.1  paxillin isoform X24

    UniProtKB/TrEMBL
    A0A2I3S8V3, A0A2J8MDT8, A0A6D2WJ48

  21. XM_063785073.1 → XP_063641143.1  paxillin isoform X6

  22. XM_063785088.1 → XP_063641158.1  paxillin isoform X22

    UniProtKB/TrEMBL
    A0A2I3RLQ8

  23. XM_009426378.4 → XP_009424653.1  paxillin isoform X5

    UniProtKB/TrEMBL
    A0A2I3S2N0
    Conserved Domains (5) summary
    cd09338
    Location:964 → 1016
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09407
    Location:905 → 956
    LIM2_Paxillin; The second LIM domain of paxillin
    cd09411
    Location:1023 → 1074
    LIM4_Paxillin; The fourth LIM domain of Paxillin
    cd09336
    Location:846 → 898
    LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    pfam03535
    Location:52 → 251
    Paxillin; Paxillin family

  24. XM_054663667.2 → XP_054519642.1  paxillin isoform X11

  25. XM_009426376.4 → XP_009424651.1  paxillin isoform X3

    UniProtKB/TrEMBL
    A0A2I3S2N0
    Conserved Domains (5) summary
    cd09338
    Location:967 → 1019
    LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
    cd09407
    Location:908 → 959
    LIM2_Paxillin; The second LIM domain of paxillin
    cd09411
    Location:1026 → 1077
    LIM4_Paxillin; The fourth LIM domain of Paxillin
    cd09336
    Location:849 → 901
    LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    pfam03535
    Location:55 → 254
    Paxillin; Paxillin family

  26. XM_063785091.1 → XP_063641161.1  paxillin isoform X24

    UniProtKB/TrEMBL
    A0A2I3S8V3, A0A2J8MDT8, A0A6D2WJ48

  27. XM_063785074.1 → XP_063641144.1  paxillin isoform X6

  28. XM_063785090.1 → XP_063641160.1  paxillin isoform X24

    UniProtKB/TrEMBL
    A0A2I3S8V3, A0A2J8MDT8, A0A6D2WJ48

  29. XM_054663664.2 → XP_054519639.1  paxillin isoform X6

  30. XM_063785084.1 → XP_063641154.1  paxillin isoform X18

  31. XM_063785089.1 → XP_063641159.1  paxillin isoform X23

Nucleotide Protein
Heading Accession and Version

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