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RAP1B RAP1B, member of RAS oncogene family [ Pan troglodytes (chimpanzee) ]

Gene ID: 452065, updated on 3-Apr-2024

Summary

Official Symbol
RAP1Bprovided by VGNC
Official Full Name
RAP1B, member of RAS oncogene familyprovided by VGNC
Primary source
VGNC:VGNC:10515
Locus tag
CK820_G0041494
See related
Ensembl:ENSPTRG00000005197
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See RAP1B in Genome Data Viewer
Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (75349319..75399633)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (73964592..74014765)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene 26S proteasome regulatory subunit 10B-like Neighboring gene small ribosomal subunit protein uS2-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene ATP synthase subunit d, mitochondrial-like Neighboring gene uncharacterized LOC134807583 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene nucleoporin 107

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Rap protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to cAMP IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of synaptic vesicle exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ras-related protein Rap-1b
NP_001092015.1
XP_009424050.1
XP_009424051.1
XP_009424052.1
XP_009424053.1
XP_016778072.1
XP_016778074.1
XP_063640845.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098545.1NP_001092015.1  ras-related protein Rap-1b

    See identical proteins and their annotated locations for NP_001092015.1

    Status: PROVISIONAL

    Source sequence(s)
    AB222125
    UniProtKB/Swiss-Prot
    A5A6J7
    UniProtKB/TrEMBL
    A0A2J8K4V3, A0A2J8K4W0, A0A663DGR4, K7CP55
    Related
    ENSPTRP00000070769.1, ENSPTRT00000110714.1
    Conserved Domains (1) summary
    cd04175
    Location:3167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    75349319..75399633
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009425775.4XP_009424050.1  ras-related protein Rap-1b isoform X1

    See identical proteins and their annotated locations for XP_009424050.1

    UniProtKB/Swiss-Prot
    A5A6J7
    UniProtKB/TrEMBL
    A0A2J8K4V3, A0A2J8K4W0, A0A663DGR4, K7CP55
    Conserved Domains (1) summary
    cd04175
    Location:3167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms
  2. XM_016922585.3XP_016778074.1  ras-related protein Rap-1b isoform X4

    UniProtKB/TrEMBL
    A0A2I3SQ18, A0A2J8K4V6, A0A2J8K4W6, A0A6D2XP00
    Related
    ENSPTRP00000078611.1
    Conserved Domains (1) summary
    cl38936
    Location:3109
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_009425776.5XP_009424051.1  ras-related protein Rap-1b isoform X2

    See identical proteins and their annotated locations for XP_009424051.1

    Conserved Domains (2) summary
    smart00010
    Location:2145
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
    cl21455
    Location:3144
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_009425777.4XP_009424052.1  ras-related protein Rap-1b isoform X3

    See identical proteins and their annotated locations for XP_009424052.1

    UniProtKB/TrEMBL
    A0A2J8K4U9, A0A2J8K4W8, A0A6D2WBV9
    Conserved Domains (1) summary
    cl38936
    Location:3125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  5. XM_063784775.1XP_063640845.1  ras-related protein Rap-1b isoform X4

    UniProtKB/TrEMBL
    A0A2I3SQ18, A0A2J8K4V6, A0A6D2XP00
  6. XM_016922583.4XP_016778072.1  ras-related protein Rap-1b isoform X2

    Conserved Domains (2) summary
    smart00010
    Location:2145
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
    cl21455
    Location:3144
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  7. XM_009425778.4XP_009424053.1  ras-related protein Rap-1b isoform X3

    See identical proteins and their annotated locations for XP_009424053.1

    UniProtKB/TrEMBL
    A0A2J8K4U9, A0A2J8K4W8, A0A6D2WBV9
    Related
    ENSPTRP00000008828.4
    Conserved Domains (1) summary
    cl38936
    Location:3125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases