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CDK4 cyclin dependent kinase 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452025, updated on 29-Mar-2024

Summary

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Official Symbol
CDK4provided by VGNC
Official Full Name
cyclin dependent kinase 4provided by VGNC
Primary source
VGNC:VGNC:8366
Locus tag
CK820_G0035445
See related
Ensembl:ENSPTRG00000005147
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (38279836..38284067)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (36949427..36953773)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene methyltransferase 1, tRNA methylguanosine Neighboring gene cytochrome P450 family 27 subfamily B member 1 Neighboring gene membrane associated ring-CH-type finger 9 Neighboring gene tetraspanin 31 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Neighboring gene OS9 endoplasmic reticulum lectin Neighboring gene large ribosomal subunit protein uL13-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to organic substance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 4
XP_509173.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    38279836..38284067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_509173.8 → XP_509173.2  cyclin-dependent kinase 4

    See identical proteins and their annotated locations for XP_509173.2

    UniProtKB/TrEMBL
    A0A2J8KVV7, A0A6D2XU49, H2QZZ4
    Related
    ENSPTRP00000039845.4
    Conserved Domains (1) summary
    cl21453
    Location:5 → 295
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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