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LRP1 LDL receptor related protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452006, updated on 17-Aug-2024

Summary

Official Symbol
LRP1provided by VGNC
Official Full Name
LDL receptor related protein 1provided by VGNC
Primary source
VGNC:VGNC:5459
Locus tag
CK820_G0035479
See related
Ensembl:ENSPTRG00000005122
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See LRP1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
89
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (38819789..38905100, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (37489642..37574931, complement)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene serine hydroxymethyltransferase 2 Neighboring gene neurexophilin 4 Neighboring gene signal transducer and activator of transcription 6 Neighboring gene NGFI-A binding protein 2 Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene myosin IA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in plasma membrane PubMed 
part_of receptor complex PubMed 

General protein information

Preferred Names
prolow-density lipoprotein receptor-related protein 1
Names
low density lipoprotein receptor-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    38819789..38905100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016924881.4XP_016780370.1  prolow-density lipoprotein receptor-related protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3S3K1, A0A2J8KWD1, A0A2J8KWD7, A0A6D2X5U5
    Related
    ENSPTRP00000071154.1
    Conserved Domains (10) summary
    smart00192
    Location:34933526
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:30943136
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:29823011
    EGF_CA; Calcium-binding EGF-like domain
    cd00112
    Location:35753609
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00058
    Location:40134053
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl00104
    Location:71104
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam12662
    Location:29622985
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:807842
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:140187
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl26742
    Location:22532463
    SGL; SMP-30/Gluconolaconase/LRE-like region
  2. XM_016924882.4XP_016780371.1  prolow-density lipoprotein receptor-related protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8KWD7
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