SP1 Sp1 transcription factor [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: SP1provided by VGNC
Official Full Name: Sp1 transcription factorprovided by VGNC
Primary source: VGNC:VGNC:5594
Locus tag: CK820_G0039535
See related: Ensembl:ENSPTRG00000005014
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	10	NC_072408.2 (42448019..42486561, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	12	NC_072410.1 (41122228..41160687, complement)

Chromosome 10 - NC_072408.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-35173 (e-PCR)
- UniSTS:3622

SHGC-33077 (e-PCR)
- UniSTS:14887

G15947 (e-PCR)
- UniSTS:60231

RH46968 (e-PCR)
- UniSTS:69549

GDB:384842 (e-PCR)
- UniSTS:157105

PMC114562P1 (e-PCR)
- UniSTS:270269

SP1_2361 (e-PCR)
- UniSTS:281027

RH65088 (e-PCR)
- UniSTS:89838

RH93219 (e-PCR)
- UniSTS:87025

A006M45 (e-PCR)
- UniSTS:25593

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription factor Sp1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

42448019..42486561 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003313665.6 → XP_003313713.1 transcription factor Sp1 isoform X2

See identical proteins and their annotated locations for XP_003313713.1

UniProtKB/TrEMBL

A0A2I3RCN7, A0A2J8KD37, A0A6D2XUV9, H2Q623

Related

ENSPTRP00000008536.4

Conserved Domains (3) summary

sd00017
Location:629 → 651

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:687 → 709

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:673 → 696

zf-H2C2_2; Zinc-finger double domain
XM_016923339.4 → XP_016778828.1 transcription factor Sp1 isoform X4

UniProtKB/TrEMBL

A0A2I3RCN7

Conserved Domains (4) summary

COG5048
Location:594 → 665

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:581 → 603

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:639 → 661

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:625 → 648

zf-H2C2_2; Zinc-finger double domain
XM_054663295.2 → XP_054519270.1 transcription factor Sp1 isoform X1
XM_054663297.2 → XP_054519272.1 transcription factor Sp1 isoform X3