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WNK1 WNK lysine deficient protein kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451739, updated on 10-Apr-2024

Summary

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Official Symbol
WNK1provided by VGNC
Official Full Name
WNK lysine deficient protein kinase 1provided by VGNC
Primary source
VGNC:VGNC:13495
Locus tag
CK820_G0037440
See related
Ensembl:ENSPTRG00000004513
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
HSN2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (7873057..8032547)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (6518719..6678194)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene U7 small nuclear RNA Neighboring gene ninjurin 2 Neighboring gene uncharacterized LOC134807540 Neighboring gene U4atac minor spliceosomal RNA Neighboring gene uncharacterized LOC134807452 Neighboring gene RAD52 homolog, DNA repair protein Neighboring gene ELKS/RAB6-interacting/CAST family member 1 Neighboring gene uncharacterized LOC107967815

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II. Shekarabi M, et al. J Clin Invest, 2008 Jul. PMID 18521183, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).
    Title: Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of sodium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase WNK1
XP_016778014.4
XP_016778015.4
XP_016778016.4
XP_016778017.4
XP_016778018.4
XP_016778019.4
XP_016778021.4
XP_016778022.4
XP_016778024.4
XP_016778025.4
XP_016778026.4
XP_016778027.4
XP_016778028.4
XP_016778029.4
XP_016778030.4
XP_016778031.4
XP_016778032.4
XP_016778033.4
XP_016778034.4
XP_016778035.4
XP_016778040.4
XP_016778042.4
XP_016778043.4
XP_016778044.4
XP_016778045.4
XP_024203341.3
XP_054518871.2
XP_054518877.2
XP_063640812.1
XP_063640814.1
XP_063640815.1
XP_063640817.1
XP_063640818.1
XP_063640819.1
XP_063640820.1
XP_063640821.1
XP_063640822.1
XP_063640823.1
XP_063640824.1
XP_063640825.1
XP_063640826.1
XP_063640827.1
XP_063640828.1
XP_063640829.1
XP_063640830.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001185048.4 → NP_001171977.3  serine/threonine-protein kinase WNK1

    Status: PROVISIONAL

    Source sequence(s)
    JAQQLN020000010
    Related
    ENSPTRP00000007718.6, ENSPTRT00000008355.6

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    7873057..8032547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016922525.4 → XP_016778014.4  serine/threonine-protein kinase WNK1 isoform X1

  2. XM_016922528.4 → XP_016778017.4  serine/threonine-protein kinase WNK1 isoform X4

  3. XM_016922527.4 → XP_016778016.4  serine/threonine-protein kinase WNK1 isoform X3

  4. XM_016922529.4 → XP_016778018.4  serine/threonine-protein kinase WNK1 isoform X6

  5. XM_054662896.2 → XP_054518871.2  serine/threonine-protein kinase WNK1 isoform X7

  6. XM_016922532.4 → XP_016778021.4  serine/threonine-protein kinase WNK1 isoform X10

  7. XM_016922533.4 → XP_016778022.4  serine/threonine-protein kinase WNK1 isoform X11

  8. XM_016922535.4 → XP_016778024.4  serine/threonine-protein kinase WNK1 isoform X12

  9. XM_016922536.4 → XP_016778025.4  serine/threonine-protein kinase WNK1 isoform X14

  10. XM_063784742.1 → XP_063640812.1  serine/threonine-protein kinase WNK1 isoform X5

  11. XM_063784744.1 → XP_063640814.1  serine/threonine-protein kinase WNK1 isoform X9

  12. XM_063784745.1 → XP_063640815.1  serine/threonine-protein kinase WNK1 isoform X13

  13. XM_016922537.4 → XP_016778026.4  serine/threonine-protein kinase WNK1 isoform X15

  14. XM_016922538.4 → XP_016778027.4  serine/threonine-protein kinase WNK1 isoform X16

  15. XM_016922539.4 → XP_016778028.4  serine/threonine-protein kinase WNK1 isoform X17

  16. XM_063784747.1 → XP_063640817.1  serine/threonine-protein kinase WNK1 isoform X18

  17. XM_016922540.4 → XP_016778029.4  serine/threonine-protein kinase WNK1 isoform X19

  18. XM_016922541.4 → XP_016778030.4  serine/threonine-protein kinase WNK1 isoform X20

  19. XM_063784748.1 → XP_063640818.1  serine/threonine-protein kinase WNK1 isoform X21

  20. XM_016922526.4 → XP_016778015.4  serine/threonine-protein kinase WNK1 isoform X2

  21. XM_016922530.4 → XP_016778019.4  serine/threonine-protein kinase WNK1 isoform X8

  22. XM_063784749.1 → XP_063640819.1  serine/threonine-protein kinase WNK1 isoform X22

  23. XM_016922543.4 → XP_016778032.4  serine/threonine-protein kinase WNK1 isoform X24

  24. XM_063784750.1 → XP_063640820.1  serine/threonine-protein kinase WNK1 isoform X28

  25. XM_063784751.1 → XP_063640821.1  serine/threonine-protein kinase WNK1 isoform X30

  26. XM_063784756.1 → XP_063640826.1  serine/threonine-protein kinase WNK1 isoform X36

  27. XM_016922554.4 → XP_016778043.4  serine/threonine-protein kinase WNK1 isoform X39

  28. XM_063784757.1 → XP_063640827.1  serine/threonine-protein kinase WNK1 isoform X41

  29. XM_016922544.4 → XP_016778033.4  serine/threonine-protein kinase WNK1 isoform X25

  30. XM_054662902.2 → XP_054518877.2  serine/threonine-protein kinase WNK1 isoform X33

  31. XM_016922555.4 → XP_016778044.4  serine/threonine-protein kinase WNK1 isoform X40

  32. XM_063784758.1 → XP_063640828.1  serine/threonine-protein kinase WNK1 isoform X42

  33. XM_016922545.4 → XP_016778034.4  serine/threonine-protein kinase WNK1 isoform X26

  34. XM_024347573.3 → XP_024203341.3  serine/threonine-protein kinase WNK1 isoform X29

  35. XM_063784752.1 → XP_063640822.1  serine/threonine-protein kinase WNK1 isoform X31

  36. XM_063784753.1 → XP_063640823.1  serine/threonine-protein kinase WNK1 isoform X32

  37. XM_063784754.1 → XP_063640824.1  serine/threonine-protein kinase WNK1 isoform X34

  38. XM_016922551.4 → XP_016778040.4  serine/threonine-protein kinase WNK1 isoform X37

  39. XM_016922556.4 → XP_016778045.4  serine/threonine-protein kinase WNK1 isoform X43

  40. XM_063784760.1 → XP_063640830.1  serine/threonine-protein kinase WNK1 isoform X45

  41. XM_016922546.4 → XP_016778035.4  serine/threonine-protein kinase WNK1 isoform X27

  42. XM_063784755.1 → XP_063640825.1  serine/threonine-protein kinase WNK1 isoform X35

  43. XM_016922553.4 → XP_016778042.4  serine/threonine-protein kinase WNK1 isoform X38

  44. XM_063784759.1 → XP_063640829.1  serine/threonine-protein kinase WNK1 isoform X44

  45. XM_016922542.4 → XP_016778031.4  serine/threonine-protein kinase WNK1 isoform X23

RNA

  1. XR_010147726.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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