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PGR progesterone receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 451502, updated on 29-Mar-2024

Summary

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Official Symbol
PGRprovided by VGNC
Official Full Name
progesterone receptorprovided by VGNC
Primary source
VGNC:VGNC:11682
Locus tag
CK820_G0031037
See related
Ensembl:ENSPTRG00000004206
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
PR; NR3C3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (103103292..103193527, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (102331440..102422337, complement)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 42 Neighboring gene COP9 signalosome complex subunit 5 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC104001300 Neighboring gene transient receptor potential cation channel subfamily C member 6 Neighboring gene putative monooxygenase p33MONOX

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The human progesterone receptor shows evidence of adaptive evolution associated with its ability to act as a transcription factor. Chen C, et al. Mol Phylogenet Evol, 2008 May. PMID 18375150, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular steroid hormone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
progesterone receptor
Names
Nuclear receptor subfamily 3 group C member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135613.1 → NP_001129085.1  progesterone receptor

    See identical proteins and their annotated locations for NP_001129085.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ234980
    UniProtKB/Swiss-Prot
    A7X8B3
    UniProtKB/TrEMBL
    H2Q4L9
    Related
    ENSPTRP00000007237.6, ENSPTRT00000007845.6
    Conserved Domains (3) summary
    cd07074
    Location:686 → 933
    NR_LBD_PR; Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor
    cd07172
    Location:563 → 640
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02161
    Location:1 → 564
    Prog_receptor; Progesterone receptor

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    103103292..103193527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063782550.1 → XP_063638620.1  progesterone receptor isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A7X8B3.1 GenPept UniProtKB/Swiss-Prot:A7X8B3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
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