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PAK1 p21 (RAC1) activated kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451439, updated on 3-Apr-2024

Summary

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Official Symbol
PAK1provided by VGNC
Official Full Name
p21 (RAC1) activated kinase 1provided by VGNC
Primary source
VGNC:VGNC:48940
Locus tag
CK820_G0021888
See related
Ensembl:ENSPTRG00000004101
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PAK1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (79334003..79487177, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (78431053..78584203, complement)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase domain containing 4 Neighboring gene mitochondrial import receptor subunit TOM20 homolog Neighboring gene NADPH--cytochrome P450 reductase-like Neighboring gene uncharacterized LOC107967164 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 1
Names
p21 protein (Cdc42/Rac)-activated kinase 1
p21-activated kinase 1
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
XP_016777167.1
XP_016777168.1
XP_016777170.1
XP_016777171.1
XP_016777175.1
XP_016777177.1
XP_054518545.1
XP_054518546.1
XP_054518550.1
XP_063639337.1
XP_063639338.1
XP_063639339.1
XP_063639340.1
XP_063639341.1
XP_063639342.1
XP_063639343.1
XP_063639344.1
XP_063639345.1
XP_063639346.1
XP_063639347.1
XP_063639348.1
XP_063639349.1
XP_063639350.1
XP_063639351.1
XP_063639352.1
XP_063639353.1
XP_063639354.1
XP_063639355.1
XP_063639356.1
XP_063639357.1
XP_063639358.1
XP_063639359.1
XP_063639360.1
XP_063639361.1
XP_063639362.1
XP_063639363.1
XP_063639364.1
XP_063639365.1
XP_063639366.1
XP_063639367.1
XP_063639368.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    79334003..79487177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054662571.2 → XP_054518546.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  2. XM_016921679.4 → XP_016777168.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  3. XM_063783285.1 → XP_063639355.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  4. XM_063783278.1 → XP_063639348.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  5. XM_063783270.1 → XP_063639340.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  6. XM_016921686.4 → XP_016777175.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Related
    ENSPTRP00000087796.1
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  7. XM_054662570.2 → XP_054518545.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  8. XM_063783290.1 → XP_063639360.1  serine/threonine-protein kinase PAK 1 isoform X3

  9. XM_063783282.1 → XP_063639352.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  10. XM_063783294.1 → XP_063639364.1  serine/threonine-protein kinase PAK 1 isoform X3

  11. XM_063783284.1 → XP_063639354.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  12. XM_063783273.1 → XP_063639343.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  13. XM_063783283.1 → XP_063639353.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  14. XM_063783296.1 → XP_063639366.1  serine/threonine-protein kinase PAK 1 isoform X3

  15. XM_063783297.1 → XP_063639367.1  serine/threonine-protein kinase PAK 1 isoform X3

  16. XM_063783281.1 → XP_063639351.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  17. XM_063783279.1 → XP_063639349.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  18. XM_063783277.1 → XP_063639347.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  19. XM_063783267.1 → XP_063639337.1  serine/threonine-protein kinase PAK 1 isoform X1

  20. XM_063783268.1 → XP_063639338.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  21. XM_063783288.1 → XP_063639358.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  22. XM_063783272.1 → XP_063639342.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  23. XM_063783295.1 → XP_063639365.1  serine/threonine-protein kinase PAK 1 isoform X3

  24. XM_063783275.1 → XP_063639345.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  25. XM_063783286.1 → XP_063639356.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  26. XM_063783274.1 → XP_063639344.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  27. XM_063783287.1 → XP_063639357.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  28. XM_063783276.1 → XP_063639346.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  29. XM_016921678.4 → XP_016777167.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  30. XM_016921681.4 → XP_016777170.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Related
    ENSPTRP00000085990.1
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  31. XM_063783269.1 → XP_063639339.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  32. XM_063783289.1 → XP_063639359.1  serine/threonine-protein kinase PAK 1 isoform X3

  33. XM_016921682.4 → XP_016777171.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  34. XM_063783292.1 → XP_063639362.1  serine/threonine-protein kinase PAK 1 isoform X3

  35. XM_063783280.1 → XP_063639350.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  36. XM_063783293.1 → XP_063639363.1  serine/threonine-protein kinase PAK 1 isoform X3

  37. XM_063783271.1 → XP_063639341.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  38. XM_063783298.1 → XP_063639368.1  serine/threonine-protein kinase PAK 1 isoform X4

  39. XM_063783291.1 → XP_063639361.1  serine/threonine-protein kinase PAK 1 isoform X3

  40. XM_054662575.1 → XP_054518550.1  serine/threonine-protein kinase PAK 1 isoform X6

  41. XM_016921688.4 → XP_016777177.1  serine/threonine-protein kinase PAK 1 isoform X5

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBI2, A0A6D2XRU6, H2Q4G3
    Related
    ENSPTRP00000007058.4
    Conserved Domains (2) summary
    cd06647
    Location:262 → 517
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:74 → 128
    PBD; P21-Rho-binding domain
Nucleotide Protein
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