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INPPL1 inositol polyphosphate phosphatase like 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451403, updated on 3-Apr-2024

Summary

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Official Symbol
INPPL1provided by VGNC
Official Full Name
inositol polyphosphate phosphatase like 1provided by VGNC
Primary source
VGNC:VGNC:3251
Locus tag
CK820_G0047596
See related
Ensembl:ENSPTRG00000004031
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (74257496..74272759)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (73359923..73375584)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene folate receptor alpha Neighboring gene folate receptor beta Neighboring gene paired like homeobox 2A Neighboring gene uncharacterized LOC107967152 Neighboring gene docking protein 1-like Neighboring gene splicing factor U2AF 35 kDa subunit-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-polyphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    74257496..74272759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063784305.1 → XP_063640375.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3

  2. XM_508622.8 → XP_508622.2  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2

    See identical proteins and their annotated locations for XP_508622.2

    UniProtKB/TrEMBL
    A0A2I3SUQ8, A0A2J8PZT8, A0A6D2WFI3, H2Q4C6
    Related
    ENSPTRP00000006936.3
    Conserved Domains (5) summary
    cd09491
    Location:1194 → 1256
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:424 → 727
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:17 → 119
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    cl25800
    Location:902 → 1046
    GGN; Gametogenetin
    cl27966
    Location:93 → 181
    MinC; Septum formation inhibitor MinC [Cell cycle control, cell division, chromosome partitioning]

  3. XM_009423712.5 → XP_009421987.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X4

    See identical proteins and their annotated locations for XP_009421987.1

    UniProtKB/TrEMBL
    A0A2I3SUQ8
    Conserved Domains (4) summary
    cd09491
    Location:1216 → 1278
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:446 → 749
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    smart00454
    Location:1224 → 1280
    SAM; Sterile alpha motif
    cd10343
    Location:17 → 119
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)

  4. XM_054662534.2 → XP_054518509.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

Nucleotide Protein
Heading Accession and Version

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