BUB3 BUB3 mitotic checkpoint protein [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: BUB3provided by VGNC
Official Full Name: BUB3 mitotic checkpoint proteinprovided by VGNC
Primary source: VGNC:VGNC:57512
Locus tag: CK820_G0003773
See related: Ensembl:ENSPTRG00000044868
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (135237323..135248610)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (125853899..125865187)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH44567 (e-PCR)
- UniSTS:46892

RH78800 (e-PCR)
- UniSTS:39487

WI-6454 (e-PCR)
- UniSTS:19082

SHGC-34669 (e-PCR)
- UniSTS:18092

RH67968 (e-PCR)
- UniSTS:73915

SHGC-64047 (e-PCR)
- UniSTS:46781

SHGC-154541 (e-PCR)
- UniSTS:178125

RH48208 (e-PCR)
- UniSTS:32467

RH15695 (e-PCR)
- UniSTS:85471

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitotic spindle assembly checkpoint signaling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of bub1-bub3 complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
part_of mitotic checkpoint complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: mitotic checkpoint protein BUB3

Names: BUB3 budding uninhibited by benzimidazoles 3 homolog; budding uninhibited by benzimidazoles 3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

135237323..135248610

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016919552.2 → XP_016775041.1 mitotic checkpoint protein BUB3 isoform X2

UniProtKB/TrEMBL

A0A2J8PBQ4, A0A2J8PBQ7, A0A8I3B0S1, K7BAN0, K7BGR1

Conserved Domains (2) summary

sd00039
Location:17 → 54

7WD40; WD40 repeat [structural motif]

cl29593
Location:14 → 296

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_016919551.2 → XP_016775040.1 mitotic checkpoint protein BUB3 isoform X1

UniProtKB/TrEMBL

A0A2J8PBQ4, A0A2J8PBQ8, A0A6D2W8X0, K6ZVC6

Related

ENSPTRP00000086143.1

Conserved Domains (2) summary

sd00039
Location:17 → 54

7WD40; WD40 repeat [structural motif]

cl29593
Location:14 → 296

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...