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SUFU SUFU negative regulator of hedgehog signaling [ Pan troglodytes (chimpanzee) ]

Gene ID: 450699, updated on 3-Apr-2024

Summary

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Official Symbol
SUFUprovided by VGNC
Official Full Name
SUFU negative regulator of hedgehog signalingprovided by VGNC
Primary source
VGNC:VGNC:5794
Locus tag
CK820_G0004068
See related
Ensembl:ENSPTRG00000002895
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (114605924..114732375)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (105219848..105346303)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104008284 Neighboring gene chromosome 10 C10orf95 homolog Neighboring gene major facilitator superfamily domain containing 13A Neighboring gene actin related protein 1A Neighboring gene U6 spliceosomal RNA Neighboring gene tripartite motif containing 8 Neighboring gene ADP ribosylation factor like GTPase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic sequestering of transcription factor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of fused homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    114605924..114732375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054660470.1 → XP_054516445.1  suppressor of fused homolog isoform X9

  2. XM_063781127.1 → XP_063637197.1  suppressor of fused homolog isoform X2

    UniProtKB/TrEMBL
    A0A2J8PCX9, A0A803KJE2, K7DIK8

  3. XM_063781129.1 → XP_063637199.1  suppressor of fused homolog isoform X8

    UniProtKB/TrEMBL
    A0A2I3RQE6, A0A2J8PCY7, A0A6D2XLN8

  4. XM_063781126.1 → XP_063637196.1  suppressor of fused homolog isoform X1

    UniProtKB/TrEMBL
    H2Q2H8

  5. XM_063781130.1 → XP_063637200.1  suppressor of fused homolog isoform X10

  6. XM_063781131.1 → XP_063637201.1  suppressor of fused homolog isoform X11

  7. XM_016919244.3 → XP_016774733.1  suppressor of fused homolog isoform X8

    UniProtKB/TrEMBL
    A0A2I3RQE6, A0A2J8PCX7, A0A2J8PCY7, A0A6D2XLN8
    Related
    ENSPTRP00000066881.1
    Conserved Domains (2) summary
    pfam05076
    Location:64 → 240
    SUFU; Suppressor of fused protein (SUFU)
    pfam12470
    Location:253 → 433
    SUFU_C; Suppressor of Fused Gli/Ci N terminal binding domain

  8. XM_009459135.5 → XP_009457410.1  suppressor of fused homolog isoform X1

    See identical proteins and their annotated locations for XP_009457410.1

    UniProtKB/TrEMBL
    A0A2I3SA11, H2Q2H8
    Related
    ENSPTRP00000005102.4
    Conserved Domains (2) summary
    pfam05076
    Location:64 → 240
    SUFU; Suppressor of fused protein (SUFU)
    pfam12470
    Location:254 → 474
    SUFU_C; Suppressor of Fused Gli/Ci N terminal binding domain

  9. XM_054660466.2 → XP_054516441.1  suppressor of fused homolog isoform X4

  10. XM_024346569.3 → XP_024202337.1  suppressor of fused homolog isoform X13

    UniProtKB/TrEMBL
    A0A2I3SA11
    Conserved Domains (2) summary
    pfam05076
    Location:64 → 240
    SUFU; Suppressor of fused protein (SUFU)
    pfam12470
    Location:253 → 515
    SUFU_C; Suppressor of Fused Gli/Ci N terminal binding domain

  11. XM_009459136.5 → XP_009457411.1  suppressor of fused homolog isoform X12

    UniProtKB/TrEMBL
    A0A2I3SA11
    Conserved Domains (2) summary
    pfam05076
    Location:64 → 240
    SUFU; Suppressor of fused protein (SUFU)
    pfam12470
    Location:253 → 515
    SUFU_C; Suppressor of Fused Gli/Ci N terminal binding domain

  12. XM_063781128.1 → XP_063637198.1  suppressor of fused homolog isoform X6

  13. XM_016919240.4 → XP_016774729.1  suppressor of fused homolog isoform X3

    UniProtKB/TrEMBL
    A0A2I3SA11

  14. XM_016919243.3 → XP_016774732.1  suppressor of fused homolog isoform X7

    UniProtKB/TrEMBL
    A0A2J8PCX7
    Related
    ENSPTRP00000081636.1
    Conserved Domains (2) summary
    pfam05076
    Location:64 → 240
    SUFU; Suppressor of fused protein (SUFU)
    pfam12470
    Location:254 → 434
    SUFU_C; Suppressor of Fused Gli/Ci N terminal binding domain

  15. XM_016919242.4 → XP_016774731.1  suppressor of fused homolog isoform X5

    UniProtKB/TrEMBL
    A0A2J8PCX7

RNA

  1. XR_010146706.1 RNA Sequence

  2. XR_010146703.1 RNA Sequence

  3. XR_010146699.1 RNA Sequence

  4. XR_010146701.1 RNA Sequence

  5. XR_010146705.1 RNA Sequence

  6. XR_010146707.1 RNA Sequence

  7. XR_010146700.1 RNA Sequence

  8. XR_010146702.1 RNA Sequence

  9. XR_010146704.1 RNA Sequence

Nucleotide Protein
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