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VCL vinculin [ Pan troglodytes (chimpanzee) ]

Gene ID: 450531, updated on 29-Mar-2024

Summary

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Official Symbol
VCLprovided by VGNC
Official Full Name
vinculinprovided by VGNC
Primary source
VGNC:VGNC:5875
Locus tag
CK820_G0007832
See related
Ensembl:ENSPTRG00000002647
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (86221679..86340969)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (76841711..76960987)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene plasminogen activator, urokinase Neighboring gene adaptor related protein complex 3 subunit mu 1 Neighboring gene adenosine kinase Neighboring gene mitochondrial import inner membrane translocase subunit Tim9-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alpha-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell-cell contact zone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vinculin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    86221679..86340969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001147346.7 → XP_001147346.1  vinculin isoform X1

    See identical proteins and their annotated locations for XP_001147346.1

    UniProtKB/TrEMBL
    A0A2J8NU96, A0A6D2W075, K7AE07
    Related
    ENSPTRP00000066862.1
    Conserved Domains (1) summary
    pfam01044
    Location:66 → 1066
    Vinculin; Vinculin family

  2. XM_507854.8 → XP_507854.2  vinculin isoform X2

    See identical proteins and their annotated locations for XP_507854.2

    UniProtKB/TrEMBL
    A0A2J8NU87, A0A6D2WSN7, H2Q246
    Related
    ENSPTRP00000004598.3
    Conserved Domains (1) summary
    pfam01044
    Location:66 → 1134
    Vinculin; Vinculin family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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