ITGB1 integrin subunit beta 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ITGB1provided by VGNC
Official Full Name: integrin subunit beta 1provided by VGNC
Primary source: VGNC:VGNC:4717
Locus tag: CK820_G0018786
See related: Ensembl:ENSPTRG00000002413
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (45854069..45911834, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (36215962..36273779, complement)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D10S2354 (e-PCR)
- UniSTS:64314

RH47472 (e-PCR)
- UniSTS:84058

D10S2370 (e-PCR)
- UniSTS:57957

GDB:181546 (e-PCR)
- UniSTS:155272

ITGB1_1823 (e-PCR)
- UniSTS:277394

PMC59887P1 (e-PCR)
- UniSTS:273375

STS-M34189 (e-PCR)
- UniSTS:34037

RH40308 (e-PCR)
- UniSTS:92921

SHGC-32719 (e-PCR)
- UniSTS:167675

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables C-X3-C chemokine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables collagen binding involved in cell-matrix adhesion	IEA Inferred from Electronic Annotation more info	PubMed
enables fibronectin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables integrin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables laminin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell adhesion mediated by integrin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-matrix adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in integrin-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed
located_in focal adhesion	IEA Inferred from Electronic Annotation more info	PubMed
part_of integrin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: integrin beta-1

Names: integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

45854069..45911834 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016962976.4 → XP_016818465.1 integrin beta-1 isoform X2

UniProtKB/TrEMBL

A0A2J8MN19, A0A2J8MN26, A0A6D2XFT1, H2Q1T1

Conserved Domains (3) summary

smart00187
Location:34 → 464

INB; Integrin beta subunits (N-terminal portion of extracellular region)

pfam07965
Location:640 → 727

Integrin_B_tail; Integrin beta tail domain

pfam08725
Location:757 → 795

Integrin_b_cyt; Integrin beta cytoplasmic domain
XM_016962975.4 → XP_016818464.1 integrin beta-1 isoform X1

UniProtKB/TrEMBL

A0A2I3RYR8, A0A2J8MN26, A0A2J8MN39, A0A6D2XDR4

Conserved Domains (3) summary

smart00187
Location:34 → 464

INB; Integrin beta subunits (N-terminal portion of extracellular region)

pfam07965
Location:640 → 727

Integrin_B_tail; Integrin beta tail domain

pfam08725
Location:757 → 796

Integrin_b_cyt; Integrin beta cytoplasmic domain
XM_063781613.1 → XP_063637683.1 integrin beta-1 isoform X2

UniProtKB/TrEMBL

A0A2J8MN19, A0A6D2XFT1, H2Q1T1
XM_063781611.1 → XP_063637681.1 integrin beta-1 isoform X1

UniProtKB/TrEMBL

A0A2I3RYR8, A0A2J8MN39, A0A6D2XDR4
XM_063781614.1 → XP_063637684.1 integrin beta-1 isoform X2

UniProtKB/TrEMBL

A0A2J8MN19, A0A6D2XFT1, H2Q1T1
XM_507735.8 → XP_507735.3 integrin beta-1 isoform X2

UniProtKB/TrEMBL

A0A2J8MN19, A0A2J8MN26, A0A6D2XFT1, H2Q1T1

Related

ENSPTRP00000004110.3

Conserved Domains (3) summary

smart00187
Location:34 → 464

INB; Integrin beta subunits (N-terminal portion of extracellular region)

pfam07965
Location:640 → 727

Integrin_B_tail; Integrin beta tail domain

pfam08725
Location:757 → 795

Integrin_b_cyt; Integrin beta cytoplasmic domain
XM_009458229.5 → XP_009456504.1 integrin beta-1 isoform X1

UniProtKB/TrEMBL

A0A2I3RYR8, A0A2J8MN26, A0A2J8MN39, A0A6D2XDR4

Related

ENSPTRP00000069754.1

Conserved Domains (3) summary

smart00187
Location:34 → 464

INB; Integrin beta subunits (N-terminal portion of extracellular region)

pfam07965
Location:640 → 727

Integrin_B_tail; Integrin beta tail domain

pfam08725
Location:757 → 796

Integrin_b_cyt; Integrin beta cytoplasmic domain
XM_063781612.1 → XP_063637682.1 integrin beta-1 isoform X1

UniProtKB/TrEMBL

A0A2I3RYR8, A0A2J8MN39, A0A6D2XDR4