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IL1B interleukin 1 beta [ Pan troglodytes (chimpanzee) ]

Gene ID: 450200, updated on 29-Mar-2024

Summary

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Official Symbol
IL1Bprovided by VGNC
Official Full Name
interleukin 1 betaprovided by VGNC
Primary source
VGNC:VGNC:1940
Locus tag
CK820_G0052784
See related
Ensembl:ENSPTRG00000012372
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See IL1B in Genome Data Viewer
Location:
chromosome: 2A
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (10428817..10435875)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (112063116..112070153, complement)

Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase II subunit RPB4-like Neighboring gene interleukin 36 gamma Neighboring gene baculoviral IAP repeat-containing protein 8-like Neighboring gene uncharacterized LOC112208185 Neighboring gene interleukin 1 alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptor. Smith DE, et al. J Biol Chem, 2002 Dec 6. PMID 12356774

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-1 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of immature T cell proliferation in thymus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    10428817..10435875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001147075.8 → XP_001147075.1  interleukin-1 beta

    See identical proteins and their annotated locations for XP_001147075.1

    UniProtKB/TrEMBL
    A0A2J8IVU2, A0A663DG51, H2QIK6
    Related
    ENSPTRP00000021191.1
    Conserved Domains (2) summary
    smart00125
    Location:119 → 265
    IL1; Interleukin-1 homologues
    pfam02394
    Location:1 → 102
    IL1_propep; Interleukin-1 propeptide
Nucleotide Protein
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