U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MAP2K1 mitogen-activated protein kinase kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 450188, updated on 29-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
MAP2K1provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 1provided by VGNC
Primary source
VGNC:VGNC:7531
Locus tag
CK820_G0008254
See related
Ensembl:ENSPTRG00000007193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
MEK
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MAP2K1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (58384448..58484897)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (58359301..58459750)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene TIMELESS interacting protein Neighboring gene small Cajal body-specific RNA 14 Neighboring gene large ribosomal subunit protein uL6-like Neighboring gene ATP synthase subunit f, mitochondrial-like Neighboring gene large ribosomal subunit protein eL33-like Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nuclear RNA activating complex polypeptide 5 Neighboring gene ribosomal protein L4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
dual specificity mitogen-activated protein kinase kinase 1
Names
ERK activator kinase 1
MAP kinase kinase 1
MAPK/ERK kinase 1
MAPKK 1
MEK 1
NP_001009071.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009071.1 → NP_001009071.1  dual specificity mitogen-activated protein kinase kinase 1

    See identical proteins and their annotated locations for NP_001009071.1

    Status: PROVISIONAL

    Source sequence(s)
    AF143201
    UniProtKB/Swiss-Prot
    Q9XT09
    UniProtKB/TrEMBL
    A0A2I3RPN9
    Related
    ENSPTRP00000063228.1, ENSPTRT00000106642.1
    Conserved Domains (2) summary
    smart00220
    Location:68 → 361
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06650
    Location:62 → 380
    PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    58384448..58484897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XT09.3 GenPept UniProtKB/Swiss-Prot:Q9XT09

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous