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MAPK14 mitogen-activated protein kinase 14 [ Pan troglodytes (chimpanzee) ]

Gene ID: 450161, updated on 3-Apr-2024

Summary

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Official Symbol
MAPK14provided by VGNC
Official Full Name
mitogen-activated protein kinase 14provided by VGNC
Primary source
VGNC:VGNC:7197
Locus tag
CK820_G0007078
See related
Ensembl:ENSPTRG00000018097
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
CSBP1; SAPK2a
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (41897573..41980466)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (41897701..41980472)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene SRSF protein kinase 1 Neighboring gene solute carrier family 26 member 8 Neighboring gene ADP-sugar pyrophosphatase-like Neighboring gene basic proline-rich protein-like Neighboring gene mitogen-activated protein kinase 13 Neighboring gene bromodomain and PHD finger containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and polymorphism of two stress-activated protein kinase genes centromeric of the MHC: SAPK2a and SAPK4. Herbison CE, et al. DNA Seq, 1999. PMID 10727080

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase 14
Names
CSAIDS-binding protein 1
MAP kinase 14
MAP kinase p38 alpha
MAPK 14
mitogen-activated protein kinase 14A
mitogen-activated protein kinase p38 alpha
stress-activated protein kinase 2a
NP_001009065.1
XP_009449366.1
XP_009449367.1
XP_063667936.1
XP_063667937.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009065.1 → NP_001009065.1  mitogen-activated protein kinase 14

    See identical proteins and their annotated locations for NP_001009065.1

    Status: PROVISIONAL

    Source sequence(s)
    AF100545
    UniProtKB/Swiss-Prot
    Q95NE7
    UniProtKB/TrEMBL
    A0A2I3SDR9, A0A2J8NZ42, A0A663DIP8, K7BNX5
    Related
    ENSPTRP00000087556.1, ENSPTRT00000097220.1
    Conserved Domains (1) summary
    cd07877
    Location:6 → 350
    STKc_p38alpha; Catalytic domain of the Serine/Threonine Kinase, p38alpha Mitogen-Activated Protein Kinase (also called MAPK14)

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    41897573..41980466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063811866.1 → XP_063667936.1  mitogen-activated protein kinase 14 isoform X3

    UniProtKB/TrEMBL
    A0A2J8NZ41

  2. XM_009451091.4 → XP_009449366.1  mitogen-activated protein kinase 14 isoform X1

    See identical proteins and their annotated locations for XP_009449366.1

    UniProtKB/TrEMBL
    A0A2I3SDR9, A0A2J8NZ45, A0A6D2XRE1, K7AZV2
    Related
    ENSPTRP00000030915.4
    Conserved Domains (1) summary
    cd07877
    Location:6 → 350
    STKc_p38alpha; Catalytic domain of the Serine/Threonine Kinase, p38alpha Mitogen-Activated Protein Kinase (also called MAPK14)

  3. XM_063811867.1 → XP_063667937.1  mitogen-activated protein kinase 14 isoform X4

    UniProtKB/TrEMBL
    A0A2I3S4B9

  4. XM_009451092.5 → XP_009449367.1  mitogen-activated protein kinase 14 isoform X2

    See identical proteins and their annotated locations for XP_009449367.1

    UniProtKB/TrEMBL
    A0A2I3SDR9
    Conserved Domains (2) summary
    smart00220
    Location:16 → 283
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:15 → 325
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95NE7.3 GenPept UniProtKB/Swiss-Prot:Q95NE7

Gene LinkOut

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