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PRKCI protein kinase C iota [ Pan troglodytes (chimpanzee) ]

Gene ID: 450143, updated on 29-Mar-2024

Summary

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Official Symbol
PRKCIprovided by VGNC
Official Full Name
protein kinase C iotaprovided by VGNC
Primary source
VGNC:VGNC:12133
Locus tag
CK820_G0006087
See related
Ensembl:ENSPTRG00000015615
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (173374651..173460087)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (173283045..173369453)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene polyhomeotic homolog 3 Neighboring gene U6 spliceosomal RNA Neighboring gene U7 small nuclear RNA Neighboring gene SKI like proto-oncogene Neighboring gene claudin 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells. Hayase J, et al. J Cell Biol, 2013 Mar 4. PMID 23439680, Free PMC Article
  2. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C iota type
XP_016797782.1
XP_063662464.1
XP_526377.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    173374651..173460087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_526377.8 → XP_526377.3  protein kinase C iota type isoform X1

    UniProtKB/TrEMBL
    H2QNQ4
    Related
    ENSPTRP00000066943.1
    Conserved Domains (4) summary
    cd06404
    Location:120 → 202
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    smart00220
    Location:348 → 616
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05618
    Location:327 → 690
    STKc_aPKC_iota; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C iota
    pfam00130
    Location:235 → 287
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  2. XM_016942293.4 → XP_016797782.1  protein kinase C iota type isoform X2

  3. XM_063806394.1 → XP_063662464.1  protein kinase C iota type isoform X3

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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