AGT angiotensinogen [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: AGTprovided by VGNC
Official Full Name: angiotensinogenprovided by VGNC
Primary source: VGNC:VGNC:40
Locus tag: CK820_G0023088
See related: Ensembl:ENSPTRG00000002096
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: REN; SERPINA8
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (18473269..18484255)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (212839081..212850067, complement)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH91381 (e-PCR)
- UniSTS:87428

RH11822 (e-PCR)
- UniSTS:67463

G44347 (e-PCR)
- UniSTS:95134

PMC310924P1 (e-PCR)
- UniSTS:272812

G34823 (e-PCR)
- UniSTS:21944

WI-8965 (e-PCR)
- UniSTS:65748

RH76317 (e-PCR)
- UniSTS:91903

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of systemic arterial blood pressure by renin-angiotensin	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: angiotensinogen

Names: angiotensinogen (serpin peptidase inhibitor, clade A, member 8); serpin A8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001009032.1 → NP_001009032.1 angiotensinogen precursor

See identical proteins and their annotated locations for NP_001009032.1

Status: PROVISIONAL

Source sequence(s)

AF188487

UniProtKB/TrEMBL

A0A2J8M6K0, A0A6D2WMX5, H2Q1B7, K7D4U3

Related

ENSPTRP00000003543.4, ENSPTRT00000003835.4

Conserved Domains (1) summary

cd02054
Location:105 → 481

angiotensinogen; Angiotensinogen is part of the renin-angiotensin system (RAS), which plays an important role in blood pressure regulation, renal haemodynamics, fluid and electrolyte homeostasis. It is also involved in normal and abnormal growth processes. The growth ...