IFNG interferon gamma [Pan troglodytes (chimpanzee)] - Gene

Summary

Gene symbol: IFNG
Gene description: interferon gamma
Locus tag: CK820_G0041509
See related: Ensembl:ENSPTRG00000005193
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: IF2F
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	10	NC_072408.2 (74889475..74893735, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	12	NC_072410.1 (73505270..73509534, complement)

Chromosome 10 - NC_072408.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CD3(-) CD8(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma, and that IL-15 elicits IFN-gamma production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 antigen, IFN-gamma]
Title: Influence of interleukin-15 on CD8+ natural killer cells in human immunodeficiency virus type 1-infected chimpanzees.

Submit: New GeneRIF Correction

General gene information

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Markers

PMC22712P3 (e-PCR)
- UniSTS:272150

IFNG (e-PCR), detects polymorphism
- UniSTS:266297

IFNG (e-PCR), detects polymorphism
- UniSTS:480107

PMC135596P1 (e-PCR)
- UniSTS:270757

GDB:181602 (e-PCR)
- UniSTS:155309

PMC154023P1 (e-PCR)
- UniSTS:271283

IFNG_3047 (e-PCR)
- UniSTS:462268

GDB:207646 (e-PCR)
- UniSTS:156120

PMC199428P1 (e-PCR)
- UniSTS:271866

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables type II interferon receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in humoral immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon gamma

Names: IFN-gamma; immune interferon; interferon 2F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001193665.1 → NP_001180594.1 interferon gamma precursor

See identical proteins and their annotated locations for NP_001180594.1

Status: PROVISIONAL

Source sequence(s)

AF164788, JAQQLN020000010

UniProtKB/Swiss-Prot

Q9TTB0

UniProtKB/TrEMBL

A0A2J8K4Y5, A0A6D2XNN1, H2Q6F3

Related

ENSPTRP00000008822.3, ENSPTRT00000009540.4

Conserved Domains (1) summary

pfam00714
Location:15 → 154

IFN-gamma; Interferon gamma

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

74889475..74893735 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)