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CCNB3 cyclin B3 [ Canis lupus familiaris (dog) ]

Gene ID: 449494, updated on 5-Mar-2024

Summary

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Official Symbol
CCNB3provided by VGNC
Official Full Name
cyclin B3provided by VGNC
Primary source
VGNC:VGNC:38895
See related
Ensembl:ENSCAFG00845026533
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See CCNB3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (43102335..43180933)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (17340549..17389577)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (43170367..43219386)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (43088178..43137193)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (43075470..43124516)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene chloride voltage-gated channel 5 Neighboring gene microRNA mir-502 Neighboring gene A-kinase anchoring protein 4 Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene RNA-binding protein 3-like Neighboring gene U2 spliceosomal RNA Neighboring gene diacylglycerol kinase kappa Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of cyclin B3 shows an abrupt three-fold size increase, due to the extension of a single exon in placental mammals, allowing for new protein-protein interactions. Lozano JC, et al. Mol Biol Evol, 2012 Dec. PMID 22826462

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic cell cycle phase transition IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G2/mitotic-specific cyclin-B3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005763.1 → NP_001005763.1  G2/mitotic-specific cyclin-B3

    See identical proteins and their annotated locations for NP_001005763.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ833648
    UniProtKB/Swiss-Prot
    Q659K0
    UniProtKB/TrEMBL
    A0A8P0SKB3
    Related
    ENSCAFP00845036927.1, ENSCAFT00845047055.1
    Conserved Domains (2) summary
    pfam00134
    Location:1075 → 1200
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:1202 → 1318
    Cyclin_C; Cyclin, C-terminal domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    43102335..43180933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448833.1 → XP_038304761.1  G2/mitotic-specific cyclin-B3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L1L2, A0A8C0SJS5, A0A8I3SAB0, A0A8P0SKB3
    Conserved Domains (2) summary
    cd20508
    Location:1058 → 1198
    CYCLIN_CCNB3_rpt1; first cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins
    cd20510
    Location:1202 → 1316
    CYCLIN_CCNB3_rpt2; second cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins

  2. XM_038448834.1 → XP_038304762.1  G2/mitotic-specific cyclin-B3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L1L2, A0A8C0SJS5, A0A8I3SAB0, A0A8P0SKB3
    Conserved Domains (2) summary
    cd20508
    Location:1058 → 1198
    CYCLIN_CCNB3_rpt1; first cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins
    cd20510
    Location:1202 → 1316
    CYCLIN_CCNB3_rpt2; second cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins

  3. XM_038448832.1 → XP_038304760.1  G2/mitotic-specific cyclin-B3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L1L2, A0A8C0SJS5, A0A8I3SAB0, A0A8P0SKB3
    Related
    ENSCAFP00845036738.1, ENSCAFT00845046841.1
    Conserved Domains (2) summary
    cd20508
    Location:1058 → 1198
    CYCLIN_CCNB3_rpt1; first cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins
    cd20510
    Location:1202 → 1316
    CYCLIN_CCNB3_rpt2; second cyclin box found in G2/mitotic-specific cyclin-B3 (CCNB3) and similar proteins

  4. XM_038448835.1 → XP_038304763.1  G2/mitotic-specific cyclin-B3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0P1Q6
    Conserved Domains (1) summary
    cl40454
    Location:1058 → 1084
    CYCLIN_SF; Cyclin box fold superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    43088178..43137193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    43075470..43124516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    43170367..43219386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    17340549..17389577
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q659K0.1 GenPept UniProtKB/Swiss-Prot:Q659K0

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