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snrpg small nuclear ribonucleoprotein polypeptide G [ Danio rerio (zebrafish) ]

Gene ID: 447922, updated on 27-Mar-2024

Summary

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Official Symbol
snrpgprovided by ZNC
Official Full Name
small nuclear ribonucleoprotein polypeptide Gprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-105
See related
Ensembl:ENSDARG00000099667 AllianceGenome:ZFIN:ZDB-GENE-040912-105
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:103688
Summary
Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of SMN-Sm protein complex and nucleus. Predicted to be active in P granule. Is expressed in liver. Orthologous to several human genes including SNRPG (small nuclear ribonucleoprotein polypeptide G). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (33957357..33962000)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (34030826..34035469)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene coenzyme Q10A Neighboring gene si:ch211-148l7.4 Neighboring gene pyridoxal phosphate binding protein Neighboring gene uncharacterized LOC110438324 Neighboring gene transmembrane p24 trafficking protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish. Liu Y, et al. J Ophthalmol, 2015. PMID 26137319, Free PMC Article
  2. PRPF4 mutations cause autosomal dominant retinitis pigmentosa. Chen X, et al. Hum Mol Genet, 2014 Jun 1. PMID 24419317
  3. Def functions as a cell autonomous factor in organogenesis of digestive organs in zebrafish. Tao T, et al. PLoS One, 2013. PMID 23593122, Free PMC Article
  4. Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Iwanami N, et al. Cell Rep, 2016 Nov 22. PMID 27880902, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within spliceosomal snRNP assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in spliceosomal snRNP assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in P granule IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SMN-Sm protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U4 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U5 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
small nuclear ribonucleoprotein G
NP_001004660.2
NP_001290030.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004660.3 → NP_001004660.2  small nuclear ribonucleoprotein G isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2).
    Source sequence(s)
    CT025912, EH443016, EH549128
    UniProtKB/TrEMBL
    A0A8M1N2G4, F1QPY7
    Related
    ENSDARP00000133036.1, ENSDART00000172069.2
    Conserved Domains (1) summary
    cd01719
    Location:5 → 74
    Sm_G; Sm protein G

  2. NM_001303101.1 → NP_001290030.1  small nuclear ribonucleoprotein G isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 2. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 2.
    Source sequence(s)
    CT025912, EH443016, EH503641, EH549128
    UniProtKB/TrEMBL
    A0A8M1P779
    Conserved Domains (1) summary
    cd01719
    Location:5 → 60
    Sm_G; Sm protein G

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    33957357..33962000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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