gtf2h1 general transcription factor IIH, polypeptide 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gtf2h1provided by ZNC
Official Full Name: general transcription factor IIH, polypeptide 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-164
See related: Ensembl:ENSDARG00000026701 AllianceGenome:ZFIN:ZDB-GENE-040912-164
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92126
Summary: Predicted to be involved in nucleic acid metabolic process and phosphorylation of RNA polymerase II C-terminal domain. Predicted to act upstream of or within nucleotide-excision repair and transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (3196855..3217115, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (3071111..3091371, complement)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Xenophagy receptors Optn and p62 and autophagy modulator Dram1 independently promote the zebrafish host defense against Mycobacterium marinum.
Title: Xenophagy receptors Optn and p62 and autophagy modulator Dram1 independently promote the zebrafish host defense against Mycobacterium marinum.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in DNA repair	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleotide-excision repair	IEA Inferred from Electronic Annotation more info
involved_in transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIH core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIH core complex	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIH holo complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: general transcription factor IIH subunit 1

Names: p62; zmp:0000000569

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004596.1 → NP_001004596.1 general transcription factor IIH subunit 1

See identical proteins and their annotated locations for NP_001004596.1

Status: PROVISIONAL

Source sequence(s)

BC081602

UniProtKB/TrEMBL

A0A8M1N2C2, Q66I03

Related

ENSDARP00000038901.5, ENSDART00000032390.6

Conserved Domains (3) summary

smart00751
Location:101 → 153

BSD; domain in transcription factors and synapse-associated proteins

cd13229
Location:9 → 102

PH_TFIIH; Transcription Factor II H (TFIIH) Pleckstrin homology (PH) domain

pfam03909
Location:181 → 236

BSD; BSD domain