acads acyl-CoA dehydrogenase short chain [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: acadsprovided by ZNC
Official Full Name: acyl-CoA dehydrogenase short chainprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040808-64
See related: Ensembl:ENSDARG00000030781 AllianceGenome:ZFIN:ZDB-GENE-040808-64
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc44c01; zgc:92400; wu:fc44c01
Summary: Predicted to enable acyl-CoA dehydrogenase activity and butyryl-CoA dehydrogenase activity. Predicted to be involved in butyrate catabolic process and fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in short chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADS (acyl-CoA dehydrogenase short chain). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (43999267..44017652, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (44152470..44170855, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyl-CoA dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables butyryl-CoA dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-CH group of donors	IEA Inferred from Electronic Annotation more info
enables short-chain fatty acyl-CoA dehydrogenase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in butyrate catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: short-chain specific acyl-CoA dehydrogenase, mitochondrial

Names: acyl-CoA dehydrogenase, C-2 to C-3 short chain; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain

NP_001003743.1

EC 1.3.8.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003743.1 → NP_001003743.1 short-chain specific acyl-CoA dehydrogenase, mitochondrial

See identical proteins and their annotated locations for NP_001003743.1

Status: PROVISIONAL

Source sequence(s)

BC079521

UniProtKB/TrEMBL

A0A8M1N1K2, Q6AXI7

Related

ENSDARP00000014757.7, ENSDART00000014669.9

Conserved Domains (2) summary

cd01158
Location:29 → 401

SCAD_SBCAD; Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases

COG1960
Location:26 → 405

CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]